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Off-label use is when an approved medicine is prescribed for a different reason, at a different dose, or in different patient groups than originally intended. Benny Lin/Flickr

Explainer: why are off-label medicines prescribed?

The off-label use of medicines is not illegal and it doesn’t mean regulators have specifically “disapproved” its use. But there are a number of issues to consider before using a medicine off-label.
NASA artists’ interpretation of the neutron star Swift J1749.4-2807 (left) with it’s companion star (right). NASA/Goddard Space Flight Center

Explainer: what is a neutron star?

They’re are the overachievers of the universe: incredibly dense but very small when compared to others stars. So how much do we know about the extreme behaviour of neutron stars?
Dyson Heydon is facing a push to remove him as royal commissioner investigating trade union corruption. AAP/Joel Carrett

Explainer: Dyson Heydon and claims of ‘apprehended bias’

Judges and other officials – such as tribunal members and royal commissioners – must not only be impartial, they must also appear to be impartial.
Danny Nalliah’s Rise Up Australia is one example of a far-right, ‘moralistic’ party that has sprung up in recent years. AAP/Joe Castro

Explainer: Australia’s tangled web of far-right political parties

Far-right movements and parties in Australia will continue to create interest, given their policies and method of operation. Their future longevity, however, is by no means assured.
Insulin, which is used for controlling diabetes and has been in the market for 30 years, was the first biologic. Yusmar Yahaya/Flickr

Explainer: what are biologics and biosimilars?

Biologics are widely accepted as the most effective way of treating certain diseases. They have become the fastest-growing class of therapeutic compounds, with about 300 now available for human use.
‘What makes directing worthwhile are the people who you do it with.’ Jane Dempster/AAP. Bell Shakespeare's production of Tartuffe, 2014.

Theatre directing in Australia – some notes from the wings

‘Theatre directors come in two kinds: “star” and “of use”. I’m in the latter category, which means that, for any given play, there are at least three or four other directors who could do it equally well.’
Breaking down the colours in the star light can reveal more about what you are looking at. Flickr/Indigo Skies Photography

Explainer: seeing the universe through spectroscopic eyes

Astronomers can tell a whole lot more about a star or a galaxy if they break up the visible light in a rainbow of colours.
Creutzfeld-Jacob disease occurs in about one to two in every million people each year, most often in late middle-age. Andrew Mason/Flickr

Rare and deadly, Creutzfeldt-Jakob disease remains a bit of a medical mystery

News that a Sydney man has contracted Creutzfeld-Jacob disease serves to highlight that we still don’t know how to prevent a disease that most often goes unreported, and unremarked on.
The government’s bill introduces three means for revoking a dual national’s Australian citizenship under amendments to the Australian Citizenship Act. AAP/Mick Tsikas

Who exactly makes the call on conduct that revokes citizenship? New bill doesn’t say

Should the bill be enacted in its current form, Australian citizenship will be able to be stripped from dual nationals by bureaucratic determination for conduct that is defined with reference to the criminal law.
Under certain conditions, war may be morally permissible, or even necessary. EPA/Said Yusuf Warsame

How should we think about war? Understanding Just War Theory

Political leaders frequently invoke Just War Theory to ground their explanations of why they are waging war against another state and how they plan to do so. What are the key components of this moral position?
Debate over potential pollutants calls for better tools to measure air quality. Singapore Spotter/flickr

Explainer: is aircraft cabin air toxic?

Health effects from contamination on planes is controversial, not least because we don’t measure on-board air quality during ‘fume events’.
Immigration Minister Peter Dutton will have the sole power to strip dual nationals of their Australia citizenship if they are believed to be involved in terrorist activities. AAP/Dave Hunt

Explainer: what is ‘judicial review’? How does it apply to citizenship?

Simply having judicial review for the contentious power to strip citizenship from dual nationals suspected of involvement with terrorism – without independent merits review – is far from reasonable.
Bill Shorten has introduced a bill into parliament to amend the Marriage Act and allow same-sex marriage in Australia. AAP/Mick Tsikas

Explainer: how Australia can legalise same-sex marriage

The legislative reform required to allow same-sex marriage is not complicated. There is relative consensus as to how this can be achieved.
A man undergoes “xenodiagnosis” for Chagas disease in the Argentine province of Corrientes. In this procedure, uninfected triatomine bugs feed on the blood of patients. Later examination of these insects may reveal parasites acquired from infected blood. German Pomar/Reuters

Explainer: what is Chagas disease?

This parasitic infection is endemic in Central and South America, and can lead to serious health complications. Though rare in the US, incidence is starting to increase.

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