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Articles on Vaccine development

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The black-legged tick is the vector that spreads Lyme disease. Its bite can infect humans with the Borrelia burgdorferi bacterium. (Jim Gathany/CDC)

Lyme disease: The pathogen’s cunning strategies for persistent infection offer clues for vaccine development

The bacterium that causes Lyme disease is a master of disguise, changing its appearance to evade the immune system as it moves from the ticks that carry it to humans or animals.
Broad protection from a universal flu vaccine could replace seasonal flu shots. Flavio Coelho/Moment via Getty Images

How do you make a universal flu vaccine? A microbiologist explains the challenges, and how mRNA could offer a promising solution

Annual flu vaccines are in a constant race against a rapidly mutating virus that may one day cause the next pandemic. A one-time vaccine protecting against all variants could give humanity a leg up.
Imaging the proteins on the surface of HCV has been challenging because of the virus’s shape-shifting nature. Juan Gaertner/Science Photo Library via Getty Images

Scientists uncovered the structure of the key protein for a future hepatitis C vaccine – here’s how they did it

Using a Nobel Prize-winning technique called cryo-EM, researchers were able to identify potential areas on the hepatitis C virus that a vaccine could target.
Inhaled vaccine delivery could take on not only COVID-19, but also other respiratory infections, including tuberculosis. (Shutterstock)

Inhaled vaccine for COVID-19: The pandemic accelerated decades of research leading to jab-free vaccine now in human testing

An inhaled COVID-19 vaccine would go directly to where the body would use it: the mucosal surface of the airways. This could mean less waste and more benefit, lower costs and reduced side-effects.
On Dec. 8, 2020, the first members of the public were given doses of a coronavirus vaccine. AP Photo/Frank Augstein, Pool

International Statistic of the Year: Race for a COVID-19 vaccine

The coronavirus vaccine was developed faster than any vaccine in history. It took just 332 days from the first sequencing of the virus genome to the first vaccines given to the public.
The pharmaceutical industry opposes the suspension of intellectual property rights on COVID-19 vaccines and treatments, and no pharma companies have yet contributed to the COVID-19 Technology Access Pool. (Shutterstock)

Can a pharma company change? Profit, not altruism, motivates COVID-19 vaccine development

We should applaud drug companies for developing COVID-19 vaccines in record time, but let’s not be under any illusion about the profits that are motivating them.

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