Chengsheng Wu, University of California, San Diego; David Cheresh, University of California, San Diego et Sara Weis, University of California, San Diego
Some cancers are notoriously resistant to chemotherapy and not curable with surgery. Stopping tumors from adapting to the harsh microenvironments of the body could be a potential treatment avenue.
Huanhuan Joyce Chen, University of Chicago Pritzker School of Molecular Engineering et Abhimanyu Thakur, University of Chicago Pritzker School of Molecular Engineering
Many tumors have cancer stem cells that help them grow and evade treatments. Differentiation therapy forces these cells to mature, stopping growth with less toxicity than traditional treatments.
Both cancer and cancer treatment can impact someone’s ability to have biological children. It’s important to discuss fertility right after cancer diagnosis.
Click and bioorthogonal chemistry has enabled researchers to closely study how molecules work in their natural state in living organisms, with applications that span from cancer treatment to polymers.
Globally, most cancer patients die not because they don’t have access to newer drugs, but because they don’t have access to even basic treatments. Cancer groundshot aims to improve treatment access.
The COVID-19 mRNA vaccines put nanomedicine in the spotlight as a potential way to treat diseases like cancer and HIV. While the field isn’t there yet, better design could help fulfill its promise.
Drug repurposing can redeem failed treatments and squeeze out new uses from others. But many pharmaceutical companies are hesitant to retool existing drugs without a high return on investment.
Artificial cells on tiny microfluidic chips can provide early insight into how new cancer drugs behave in cells, and why certain kinds of cancer are more resistant to chemotherapy treatment.
Neutrons are useful in research and medicine. A proposed neutron production facility could help further Canadian research and provide a source of neutrons for medical purposes.