Huanhuan Joyce Chen

Specialized in tissue engineering and stem cell biology, the Joyce Chen Lab applies technical advances (e.g. human pluripotent stem cell-based modeling, organotypic tissue engineering and single cell analysis) to pursue long-standing questions in cancer research, stem cell biology and regenerative medicine. Our current main focus is to understand how cancers initiate and progress using various stages of human cells derived from pluripotent or adult stem cells, and design strategies to diagnose, categorize and treat the diseases more effectively. Another line of our work is to directly model and study human tissues or diseases “in a dish”, by in vivo molecule-mediated humanized mouse models, ex vivo organotypic re-cellularization or in vitro microfabrication.

The Chen group’s research interest is to integrate stem cell-based disease modeling, regenerative technologies, and single cell analysis to study organ damage repair, regenerative medicine, cancer, and other genetic diseases.