Caveman ethics? The rights and wrongs of cloning Neanderthals

It now appears that the scientist who seemed to be advocating that we clone Neanderthals was suggesting only that “we need to start talking about it.” Ethics is an essential part of such a conversation: assuming we can overcome the enormous technical challenges that currently bedevil any such cloning…

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Researchers decoded the whole mitochondrial DNA of five Neanderthal men, one of whom belonged to the El Sidron site (pictured) in Asturias, northern Spain, in 2009. EPA/CSIC

It now appears that the scientist who seemed to be advocating that we clone Neanderthals was suggesting only that “we need to start talking about it.” Ethics is an essential part of such a conversation: assuming we can overcome the enormous technical challenges that currently bedevil any such cloning initiative, should we do it?

Big science is expensive, and any money spent on it is money not spent elsewhere. The (perhaps many) millions of dollars required by this kind of research could be used for hospital beds, poverty alleviation or medical research. Of course, the money may come from private sources, rather than government, and private individuals may have the right to use their money in this way.

But it’s one thing to say that they have the right to spend their money in this way and quite another to say that it’s ethical to do so (there are many things we have the right to do that are nevertheless morally wrong: we can lie to one another, we can buy artworks and burn them, we can express racist or misogynist views, and so on). The very fact that research involves the expenditure of scarce resources, and therefore opportunity costs (the alternative uses we might have made of the money), means that it must have some positive value to be ethical.

What kind of positive value might justify it? Obviously, research is often justified by the benefits it promises to bring us: medical research has played an important role in extending the length and the quality of lives of human beings (and animals, too). And while it’s much harder to put a value on basic research – curiosity-driven research, it’s very plausible to think that basic research is valuable.

First, it plays an indirect role in bringing about benefits to humans and other animals: everything in science is connected, however distantly, to everything else, and deepening our knowledge about anything might enable us to develop better therapies in the long run. Second, knowledge seems to be valuable in itself: knowing more about the universe and our place in it is sufficiently important to justify expending some resources on science (and on the humanities, too).

Comparison of Neanderthal and Homo sapiens, with facts about Neanderthals from 2009. AAP Image/KRT

Will this research bring us practical benefits or deepen our knowledge? Cloning is now used in agriculture to that extent it has practical benefits (assuming – perhaps bravely – that this kind of agriculture is itself justified). It may be that solving the enormous technical challenges involved in cloning Neanderthals would contribute, in some way, to these practical applications.

More certainly, the research would produce knowledge that we currently lack. Right now, we know how to clone only in one way: by somatic cell nuclear transfer. Essentially, the process involves transferring the nucleus of a cell from one organism into the egg cell of a host organism. This gives us a cell with DNA the great majority of which comes from the animal to be cloned (only the mitochondrial DNA of the egg comes from the host). When the technique is successful, we get an animal that is genetically very similar to the original animal. Because we lack a preserved Neanderthal somatic cell, however, we can’t use this method. Instead, the research proposes synthesising a DNA cell using the near-complete Neanderthal genome. No doubt, the attempt to do so would add considerably to our knowledge of genetics.

Suppose we succeeded in cloning a Neanderthal. Then, it seems, we would gain knowledge in another way: we could observe the growing child and his or her behaviour. However, though we would certainly learn something in this way, it would be rash to think that we were learning much about Neanderthals through observing the clone. We don’t know how much of Neanderthal behaviour is dependent on environmental input, of the right kind and at the right time.

Human beings are innately disposed to learn language, but an alien who cloned a human being might not learn that fact unless they provided the right kind of environmental input (language develops given the right kind of exposure in childhood). Language use is, of course, central to the kind of social animals we are; so an alien who cloned a human being might learn relatively little about us (in fact, they may get a highly misleading picture of what human beings are like).

We run an analogous risk with the Neanderthal: we might get an extremely misleading picture of Neanderthal behaviour from a child brought up in a modern environment (even were we to try to replicate the environment in which his or her ancestors might have lived: we simply don’t know enough to get close).

The idea that we might try to replicate the environment in which Neanderthals lived brings us to the central issue concerning the ethics of this research: the welfare of the cloned individual. Neanderthals were intelligent: they made tools and may have had language; they certainly had a complex culture.

A model of an elderly Neanderthal man on display in the Neanderthal-Museum in Mettmann, Germany. EPA/FEDERICO GAMBARINI

Unlike most other animals, the cloned Neanderthal would have a grasp on how it is being treated. It would either have to be brought up in ignorance of its place in the world, or its unique position – the last representative of an extinct species, alone on the Earth – would have to be made clear to it.

Either option seems likely to cause it suffering; in the first place though the kind of isolation from others that ignorance would require; in the second case through a kind of existential loneliness. To have a flourishing life, it – like us – probably requires some kind of community in which it can take its place. We are unlikely to be able to offer the clone such a community.

Further, being a constant object of scientific curiosity is not likely to lead to a life of flourishing. At worst, it might feel like it’s the main attraction in a freak show.

Like other attempts at cloning, moreover, it’s highly unlikely we would not succeed at first try. Rather, it is likely to require many attempts. Embryos that are not viable would die early; some people would be troubled by that fact (though I am not). Even if we succeed in bringing an embryo to term, there’s a high likelihood that the infant would die soon afterwards or have significant health problems: it might well take many births to produce a relatively healthy individual. Sickness and death are major costs, borne by the cloned individual.

Finally, spare a thought for the woman who bears a cloned Neanderthal to term. She will undergo an invasive procedure, endure a pregnancy which may involve significant complications, and be herself the main attraction in a freak show. She may develop an attachment to the child, but is unlikely to ever have a normal relationship with it. Of course, any woman who participated in such research would be a volunteer, and women have the right to do what they like with their own bodies. Nevertheless, I suspect that she would herself bear significant costs.

I doubt that cloning a Neanderthal is possible anytime soon. The technical hurdles are too great. The knowledge we might gain through overcoming these hurdles, were we to succeed, would be of great intrinsic interest. But I doubt that they can justify the research, in the light of the costs that would have to be borne, especially by the cloned individual.

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7 Comments sorted by

  1. alfred venison

    records manager (public sector)

    sounds to me like a neanderthal born this way would have some natural, if not human, rights, acquired inevitably though being born into & raised within human society, and therefore, if coached & inclined to it, could arguably sue someone for wrongful birth. -a.v.

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  2. Notta Mehere

    logged in via Facebook

    with the present course of human development we'll be back to neanderthal status in no time at all. just look at the present level of government spending on education around the world ;-)

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  3. Philip Starkey

    Physics PhD Student

    You write "Big science is expensive, and any money spent on it is money not spent elsewhere. The (perhaps many) millions of dollars required by this kind of research could be used for hospital beds, poverty alleviation or medical research."

    I am greatly disturbed by the fact that this sentence is right up the front of your article. While you do later go on to discuss the possible benefits to this research (and opportunity cost), it immediately puts in the readers head the idea that money spent…

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  4. Catherine Pohlman

    Lecturer

    I could support a cloning attempt if the purpose was to try to bring the species back from extinction. Of course, that raises the question of whether we should try to resurrect an extinct species (and whether cloned individuals would really be a resurrection of that species or something else entirely). For my part, I think that we can justify bringing back an extinct species (even one that's been extinct for 30 thousand years or so), if we know (with a reasonable degree of certainty) that it is our…

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    1. Neil Levy

      logged in via Facebook

      In reply to Catherine Pohlman

      Catherine: no third condition? It is irrelevant whether the members of that species can be expected to have good or bad lives?

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    2. Catherine Pohlman

      Lecturer

      In reply to Neil Levy

      We can't guarantee that members of our own species will have good or bad lives. But if we brought back a species simply to watch it go extinct again, that might very well fall into the definition of "bad lives"...
      That said, I don't see the point in creating one clone simply for the sake of curiosity.

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  5. Alessandro Mazzi

    logged in via Facebook

    Indeed this article brings a long discussion within itself.

    First, we should consider that by cloning a sentient being we have to create the right conditions for this being to develop and grow naturally, and I DO mean naturally, with a completely unprogrammed life except for natural laws and spontaneous reactions. Not only for objective observation, but also for respecting that being.

    In this world, we cannot risk to clone a human being, of any kind (so this would be for other evolutions of…

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