This article greeted my tragically decaffeinated gaze this morning as I fired up the computer at work. You’d have to be concerned about a senior drug and alcohol clinician like Alex Wodak saying something like ‘We’ve got a hell of a problem’ with prescription painkillers. Especially when that respected clinician writes for this very website!
As with all medical stories patients ask me about, I thought I’d find the actual source of the reporting. Turns out it was this report from the National Drug and Alcohol Research Centre (NDARC). This is a collation of the deaths in Australia related to opioid overdose over the last few years. It is worth looking hard at the methodology behind such reports, as they are not subject to the same peer review process as journal articles.
Before getting to the conclusions, my usual process is to check whether I even believe the assumptions the researcher has made. If some of them are a stretch, have they acknowledged this? Looking at this report, I see that there are some significant assumptions, and that there is a whole section, entitled ‘Notes on Findings’ with just such a discussion. So far, so good. The notes point out that there have been some changes in the way that overdose deaths are recorded, and that this may mean that between some states and some years, we may not be comparing apples with apples. Leaving these reservations aside, is it possible to get a better feel for the scope of the problem? Are we on the way to a public health disaster like the US?
I have to say I’m concerned about the rate of opioid-related deaths in Australia. But perhaps not as worried as I am about the road toll. The number of deaths from transport accidents in 2011 was 1,291, which represented a fall of 4.4 percent from 2010, and a full third of the total from a much smaller population in the early 1970s. This compares to 551 for opioid-related deaths in 2008, with projected rates of 612 for 2009 and 705 in 2010 awaiting formal confirmation. This also includes a fair chunk of deaths from heroin overdose, at rates that have been stable at a lowish level since the heroin drought of 2001 began.
The highest rate of deaths due to opioid overdose was during the late 1990s from heroin overdoses. Those peak rates were around double the number of deaths that we currently are recording, and are still well below the States where opioid overdoses rank just behind motor vehicle crashes as a cause of death in young and middle-aged adults. The US has around 14 times the population of Australia (311 million vs 22 million) but it has 60 times the number of overdose deaths (37,000 vs 612 in 2009).
So what do we have going in our favour? Stricter advertising and sales controls on prescription drugs for a start. More lenient marijuana and alcohol laws for another, though this is just my speculation.
On the other hand we have thousands of GPs who feel poorly equipped to know how to prescribe these drugs appropriately. We have minimal enforcement of opioid regulations except against those who are already using them legally. We have a lack of community awareness that the right to pain relief needs to be coupled with the responsibility of being an informed and disciplined consumer. We also have a real lack of awareness of the long-term health penalties that go with medium or high-dose opioid use, even for therapeutic purposes.
We have a resounding absence of leadership federally on the issue of centralized monitoring of opioid scripts and who is writing them. Despite much fanfare when announced the $5 million Electronic Recording and Reporting of Controlled Drugs system remains a spectral presence, the merest phantasm of a useful product. Such systems have been shown to be effective at reducing aberrant prescribing while not affecting legitimate pain patients, but it seems that even this basic and comparatively cheap measure is beyond our health bureaucrats to implement. It was supposed to begin in July, but it’s now October and we still don’t have any news about a rollout…
So while I don’t expect this very complex and nuanced problem to be fixed any time soon, it helps to know that we’re not as bad as some news columnists would have you believe. The solutions that will reduce the availability of trafficked prescription opioids are not overly complicated. They do however some money to be spent in an area where there is no real electoral payoff. They also require a culture change in education of health professionals and the community to provide accurate and nonjudgmental information about the potential benefits and harms of medium or long-term use of opioid anagesics.
Addicts, abusers and the anxious will always tend to prefer opioids because of the effects they can have on their brains. Some will demand them to treat pain even when they aren’t helping because they have been raised to believe that there should be a pill for every ill. Most people, in my experience, have a healthy attitude to painkillers. They want them to work when they take them, and they want to be off them when they aren’t necessary anymore. For the minority who can’t control their intake of prescription opioids, the answer is in having GPs who understand these drugs and prescribe them according to best practice, backed up by pharmacists who have the training and electronic capability to monitor their supply and spot those gaming the system for criminal purposes. Penalties for prescription drug trafficking should be harsher than for illicit drugs, to ensure that it becomes a high-risk decision for those better-organized criminal types looking for an easy buck. Potentially unpopular legislation is therefore part of the regulatory solution to the problem.
Simple, isn’t it?
william hollingsworth
student flinders university
Worst comment I have read yet on the conversation.Do you really understand the value of opioids to long term chronic pain sufferers? As the only pain relief that works for many sufferers, the battering around the head with tales of perceived woes of their drug use only increases their pain. What is it with the moralist stand that so many "Pain specialists" have with opoids? Your article makes GP's sound like ninny s and if there are no long term studies on extended usage, which I am sure there are, how about examining the many life time users of opoids who can,t survive without them.Very strict procedures are in place to receive a prescription.Your article does not give me the impression that you have much knowledge on the subject or that you have had one to one contact with chronic pain sufferers.My experience of pain clinics is that they cause pain.When I wish for moral counsel I would go elsewhere.
Michael Vagg
Clinical Senior Lecturer at Deakin University School of Medicine & Pain Specialist at Barwon Health
Thanks William and Elizabeth for your comments.
While I've been accused of many things before, I have to say that these are new ones for me. Given that I spend around 30 hours a week in face-to-face appointments with people who have chronic pain I think I have a better understanding than most of the value of these drugs to chronic pain sufferers.
However, it is part of being a responsible clinician to be aware of the harm you can do as well as the benefits. For every patient I see who reduces…
Read moreelizabeth merrilees
AOD Clinician
while i might not write as strongly as william, i agree that the author is disregarding the genuine need for significant pain relief in the population.
while in my experience some GPs are ninnies, they are not causing this problem, and the glaring media attention over the abuse of prescription analgesia is causing vast grief to a lot of chronic pain sufferers who are being suddenly exited from pain relief regimes, leading to withdrawal, agony, guilt, shame and worse.
and the argument disregards those who may experience physical dependence but have physical need for pain relief.
are we going to cancel access to Ventolin due to physical dependence? "it's not the same!" try the agony and then ask yourself the question.
try being told that while you do have an anal fistula, you clearly also have a dependence on pain relief so it must be stopped. can't happen? has.
Sheena Burnell
Observer
Michael this is an excellent article, and contrary to your detractors I thought you presented a cogent summation of a difficult clincial and general societal problem. I have had recent experience rtrying to set up and run a pain clinic in China and the differences are staggering. Such is the fear of a narcotically-addicted population that opioids if available at all, are rarely if ever prescribed for any type of pain and the overall approach to pain management is a mixture of heavy government control…
Read moreMichael Vagg
Clinical Senior Lecturer at Deakin University School of Medicine & Pain Specialist at Barwon Health
Thanks for the feedback Sheena! You have a very interesting perspective compared to most of us. It's easy to forget that something like 10% of the world population uses 95% of the prescription opioids, with North America and Europe being responsible for almost all that consumption.
Adequate treatment of chronic pain is a fundamental right according to the Declaration of Montreal, and the developing world can learn from the mistakes that have already been made in industrialized countries.
william hollingsworth
student flinders university
Hi Michael
Read moreI still don't think you quite get it.I don't discount your theoretical
knowledge or a genuine wish on your part to help patients but to
say that after 5-10 years you must stop using opioids is nonsensical.
If they are the only drug that gives effective pain relief why
should't you take them for as long as necessary.We are not talking
about patients with a sprained back ,but those people who have a
lifelong debilitating disease such as rheumatoid arthritis.There is no
cure for…
Sheena Burnell
Observer
William I think your comment about China is insensitive and glib, rightly or wrongly both Opium Wars have indeed left deep scars on Chinese society which inform all teaching of modern Chinese history today. and no doubt their attitude towards this class of drugs, However the problems with their medical system are much deeper and extend to a broad range of economic, social and cultural issues. And my understanding from the title of the article is that it is a discussion regarding all aspects of the prescription drug use/abuse issue, including the illicit use of such prescriptions. Although I realise you are conversing with the author of the article on your own issues, may I point out that I was responding not just to you and another readers' comments but also to some of the broader issues raised in the article in general. Either way I think I am quite entitled to comment regardless of the parameters of your discussion.
Sue Ieraci
Public hospital clinician
WIlliam Hollingsworth says, to the author ".I don't discount your theoretical
knowledge or a genuine wish on your part to help patients..."
As Sheena says, "insensitive and glib".
Michael Vagg is a clinical pain specialist - his job involves helping people with the most difficult painful conditions who have been unable to be helped by other measures. Ihardly think this limits him to "theoretical knowledge", but to real-life clinical experience, with responsibility for outcomes.
Painaustralia
logged in via Twitter
Let’s tackle the opioid issue in a rational way.
The recent National Drug and Alcohol Research Centre (NDARC) report which raises alarm about the growing numbers of deaths from prescription opioids, must be viewed in the context of the much bigger issue – the millions of Australians whose lives are severely affected by chronic pain.
Whist 500 plus opioid deaths a year is indeed tragic, for the lives lost and the grief of families, the number of young people whose lives are ruined because…
Read moreTracy Soh
Addiction Medicine Physician
Thankyou Michael for this clear and balanced article.
The challenge with opiates is to ensure that people who legitimately need medication can receive their medication in a safe and responsible manner, and to restrict access to these potentially dangerous medications from those for whom they are not suitable or those who misuse them. A realtime prescription monitoring system is one resource that can help prescribers deal with narcotics more safely, as is better access to pain specialists and addiction…
Read moreSheena Burnell
Observer
Tracy while in an ideal world I would heartily agree with all your comments, the reality for many pain patients is a little different- which is evident even reading the few comments attached to this article. Treatment of chronic pain refractory to non-opioid analgesia is an area more difficult and more emotive than most in medicine as pain is something which everybody experiences in an utterly individual way. Additionally our society attaches significant value to the alleviation of such pain (as opposed for example to China) rendering the alleviation of pain both ethically and morally pressing. Even though your key concerns are quite valid and a very good blueprint for best practice, they may not be relevant for a proportion of patients dealing with chronic intractable pain. I am not for one minute advocating the use of opioids for chronic pain, however this a highly nuanced and difficult area of medicine and I thought Michael's article dealt with this very well.
Tracy Soh
Addiction Medicine Physician
Sheena, I agree the article covered the issues well. I simply believe it is important to differentiate between taking a patient's symptoms seriously, and handing out opiates.
Michael Vagg
Clinical Senior Lecturer at Deakin University School of Medicine & Pain Specialist at Barwon Health
I wouldn't disagree at all with Tracy, apart from pointing out that as long as long-term opioid therapy is tied to functional gains and appropriate screening for endocrine and other longer-term side effects is carried out, it is reasonable to use it in selected patients. Coming from an addiction perspective, I suspect her view of opioid chronic pain therapy is as jaundiced as mine is of back surgery! I freely admit that I only see people whose operations have gone badly, and I sometimes wonder if…
Read moreSheena Burnell
Observer
Tracy good point, and may I say how lucid and clear your original comments were, you obviously have a huge amount of experience in this area and its great to have your perspective on this forum.
william hollingsworth
student flinders university
Dear Sheena I hope you never experience any chronic pain in your life as you may be forced to eat your own words.How could you not advocate opoids for chronic pain sufferers? Far from being glib and insensitive I am being honest ,if the Chinese have a problem with opoid use they need to come up with an humane and scientific solution to its use which is not the one they obviously follow now.We treat animals with more respect than humans in many areas including pain relief and death.
Sheena Burnell
Observer
William I think if you read all of my comments, including my reply to Tracy Soh, you'll find that this is exactly what I AM saying, that there are some chronic pain patients for whom opioids may in fact be the only solution despite our being aware that this is far from an ideal situation. I also realise from your responses that this is emotive subject for you, however please try to remain respectful of other's views in your replies, Michael's article and several of the replies have been thoughtful and balanced however if you read what is being said more closely you will realise that none of us are claiming to have the perfect solution to this difficult clinical problem.