T cells recognize and kill cancer cells but quickly lose their effectiveness. This fast dysfunction may help explain why immunotherapy doesn’t lead to long-term remission for many patients.
Gregory Allen, University of California, San Francisco
Immunotherapy has the potential to eliminate tumors, but works best for select patients. Engineering T cells to bypass cancer’s defenses could help expand treatment eligibility to more patients.
October is awash in seas of pink T-shirts, balloons and ribbons in honor of Breast Cancer Awareness Month. But this messaging fails to recognize people who are not cured of the disease.
Aslan Mansurov, University of Chicago Pritzker School of Molecular Engineering
One promising cancer treatment has been in the works for decades, but severe side effects have kept it out of the clinic. A reengineered version may offer a way to safely harness its potent effects.
Researchers are trying to boost the power of our immune system by genetically altering our white blood cells and transforming them into super-soldiers to fight cancer.
Yinghong Wang, The University of Texas MD Anderson Cancer Center
Cancer immunotherapy is a revolutionary treatment for many but it can cause nasty side effects like inflammation of the colon that can derail treatment. Could the solution be a fecal transplant?
James Allison and Tasuku Honjo won the 2018 Nobel Prize in Physiology or Medicine for encouraging immune cells to attack cancer. See how their work has revolutionized cancer therapies and medicine.
Some argue the current system of subsidising drugs in Australia needs changing to accommodate new cancer therapies. But two recent drug listings show the current system is working perfectly well.
’Tis the season for listicles rounding up the stories of the year. So with, the authority vested in me, here is a selection of six top, bottom and forgotten science stories of 2014. Bounciest landing The…
Associate Professor of Microbiology and Immunology at Emory University and Adjunct Professor Microbiology and Molecular Genetics, University of Pittsburgh