Switching off essential to brain development

Neuroscientists found the “off switch” for nerve cell formation, advancing the possibility of brain cell regeneration.

The Monash University study discovered the transcription factor RP58, which is responsible for switching off stem cells in order to control the position of neurons within the brain.

Previous studies have shown the existence of an “on switch”, which starts the transformation of stem cells into neurons.

Researchers believe the discovery demonstrates that the developing brain requires both an on and off function in order to be assembled properly. The discovery could be used to treat brain disorders and injuries.

Read more at Monash University

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