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Articles on Opioid epidemic

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Community researchers discuss the impact of brain injury at BC Consensus Day at the University of Victoria. As many as 600,000 overdose-related brain injuries have occurred in Canada during the toxic drug crisis. (Mauricio A. Garcia-Barrera)

Brain injury after overdose is a hidden epidemic: Recognizing and treating the survivors of the toxic drug crisis

The toxic drug crisis is not only about fatalities. A much larger number of people survive overdoses, and are left with brain injuries. A national strategy to support and treat them is crucial.
Democrats and Republicans are equally less likely to support a drug treatment clinic if it’s in their neighborhood. Can Merey/picture alliance via Getty Images

How opioid treatment centers can overcome bipartisan NIMBYism to build local support

A Philadelphia neighborhood is pushing back against the city’s plan to expand an existing shelter to serve people in active addiction.
Drugs used to treat alcohol use disorder have been on the market for decades but are rarely prescribed. Krit of Studio OMG/Moment via Getty Images

Alcohol use disorder can be treated with an array of medications – but few people have heard of them

Alcohol is responsible for more deaths than overdoses from opioids and all other substances combined, yet less than 10% of people with alcohol use disorder receive treatment.
Substance use during pregnancy can lead to a broad array of harmful effects. Liudmila Chernetska/iStock via Getty Images Plus

Hundreds of thousands of US infants every year pay the consequences of prenatal exposure to drugs, a growing crisis particularly in rural America

Many people wrongly assume that cannabis use during pregnancy is safe. Research is increasingly documenting a host of serious health harms from prenatal exposure to cannabis and other substances.
Opioids can help reduce the amount of medication needed to achieve anesthesia. gpointstudio/iStock via Getty Images Plus

Why opting out of opioids can be dangerous in the operating room

Non-opioid directives allow patients to refuse opioids in all health care settings. For surgical procedures that require anesthesia, however, this may do more harm than good.
Naloxone can prevent deaths from opioid overdose, but there is no way to reverse the effects of benzodiazepine overdose without risk. (THE CANADIAN PRESS/Jonathan Hayward)

Benzo-dope’ may be replacing fentanyl: Dangerous substance turning up in unregulated opioids

Fentanyl adulteration led to the replacement of heroin in the unregulated drug supply of British Columbia. Now that benzodiazepines are present in many opioids, are we headed towards a ‘new normal?’
One potential way to make opioids less addictive is to make them target injured tissue rather than the healthy brain. PM Images/Photodisk via Getty Images

Designing less addictive opioids, through chemistry

While the COVID-19 pandemic raged on, the opioid epidemic got worse as drug overdose deaths soared. New research proposes a way to chemically modify opioids to reduce the risk of addiction.

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