Gene profile for Crohn’s disease identified

US researchers have identified specific gene expressions and microbes associated with the inflammatory bowel disease Crohn’s disease.

The researchers compared the intestines of healthy patients to 359 children with Crohn’s disease.

In the Crohn’s patients they found altered expression of two genes known as DUOX2 and APOA1, along with a distinct microbial community.

The researchers suggested that together, this gene expression and microbial abundance could be used to predict clinical outcomes in patients with Crohn’s disease.

Read more at Cincinatti Children's Hospital Medical Centre