The liver – an organ never before considered in weight management – can directly talk to the brain to control the amount of food we eat.

Research on mice found that over-expression of an enzyme called FBPase in the liver resulted in 50% less fat, and the subjects at less food than mice without the enzyme.

Previously, too much FBPase was considered bad for health, and promoted diabetic symptoms.

Results found the enzyme triggered appetite influencing hormones instead, and reduced genes in the brain responsible for increased food intake.