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Deep Jyoti Bhuyan

Research Fellow in Healthy Ageing at NICM Health Research Institute, Western Sydney University

I find the quote “the role of the infinitely small in nature is infinitely large” by Louis Pasteur immensely inspiring ever since my first introduction to science back in high school. This quote encapsulates the true essence of gut microbiome research. I am a Research Fellow at NICM Health Research Institute, Western Sydney University and my research is centred on understanding the role of the gut microbiome in the occurrence, treatment and prognosis of cancer to define gut-microbiota-focused therapeutic strategies. My research group is also investigating how natural bioactive compounds interact with standard drugs and how these interactions can be utilised in formulating novel treatment options for infectious diseases and cancer.
My PhD research at the University of Newcastle highlighted the therapeutic role of antioxidants from Australian Eucalyptus as anticancer agents for pancreatic malignancies. Before coming to Australia, I worked as a Senior Research Fellow at the Assam Agricultural University on a National Agricultural Innovation Project funded by the Indian Council of Agricultural Research. That project looked at the therapeutic benefits and probiotic activity of traditional North-East Indian rice beer. I have published over 40 peer-reviewed journal articles and book chapters in the areas of pharmacology, gut microbiome and cancer. My research has attracted several awards, grants and fellowships since 2011 including the NICM Health Research Institute (Western Sydney University) excellence as an Early Career Researcher award in 2020 and the Western Sydney University Research Support Program Fellowship in 2021.

Experience

  • 2021–present
    Research fellow, Western Sydney University
  • 2018–2021
    Postdoctoral research fellow, Western Sydney University
  • 2014–2018
    Part Time Lecturer, University of Newcastle
  • 2011–2013
    Senior research fellow, Assam Agricultural University

Education

  • 2018 
    University of Newcastle, PhD in Food Science
  • 2010 
    VIT University, MSc Applied Microbiology
  • 2008 
    Bangalore University, BSc Biotechnology

Publications

  • 2022
    The role of key gut microbial metabolites in the development and treatment of cancer, Gut Microbes
  • 2022
    Onion and garlic polysaccharides: A review on extraction, characterization, bioactivity, and modifications, International Journal of Biological Macromolecules
  • 2022
    Gut Metabolites and Breast Cancer: The Continuum of Dysbiosis, Breast Cancer Risk, and Potential Breast Cancer Therapy, International Journal of Molecular Sciences
  • 2022
    Australian native fruits and vegetables: Chemical composition, nutritional profile, bioactivity and potential valorization by industries, Critical Reviews in Food Science and Nutrition
  • 2022
    Guava (Psidium guajava L.) seed: A low-volume, high-value byproduct for human health and the food industry, Food Chemistry
  • 2022
    A Comprehensive Review on the Techniques for Extraction of Bioactive Compounds from Medicinal Cannabis, Molecules
  • 2021
    Synergistic Interactions of Cannabidiol with Chemotherapeutic Drugs in MCF7 Cells: Mode of Interaction and Proteomics Analysis of Mechanisms, International Journal of Molecular Sciences
  • 2021
    The complex interplay of gut microbiota with the five most common cancer types: From carcinogenesis to therapeutics to prognoses, Critical Reviews in Oncology/Hematology
  • 2021
    Tomato (Solanum lycopersicum L.) seed: A review on bioactives and biomedical activities, Biomedicine & Pharmacotherapy
  • 2021
    Metabolomic Identification of Anticancer Metabolites of Australian Propolis and Proteomic Elucidation of Its Synergistic Mechanisms with Doxorubicin in the MCF7 Cells, International Journal of Molecular Sciences
  • 2021
    Organizational level responses to the COVID-19 outbreak: Challenges, strategies and framework for academic institutions, Frontiers in Communication
  • 2021
    Broad-spectrum pharmacological activity of Australian propolis and metabolomic-driven identification of marker metabolites of propolis samples from three continents, Food & Function
  • 2020
    Recovery of ergosterol and vitamin D2 from mushroom waste-Potential valorization by food and pharmaceutical industries, Trends in Food Science & Technology
  • 2019
    The Odyssey of Bioactive Compounds in Avocado (Persea americana) and Their Health Benefits, Antioxidants
  • 2018
    An Array of Bioactive Compounds From Australian Eucalypts and Their Relevance in Pancreatic Cancer Therapeutics, Pancreas
  • 2018
    Eucalyptus microcorys leaf extract derived HPLC-fraction reduces the viability of MIA PaCa-2 cells by inducing apoptosis and arresting cell cycle, Biomedicine & Pharmacotherapy