Fabien B. Vincent

Rheumatologist; PhD student, Department of Immunology and Pathology, Faculty of Medicine, Nursing and Health Sciences, Monash University

Dr Fabien Vincent is a rheumatologist specialized in autoimmunity (systemic lupus erythematosus, rheumatoid arthritis, Sjögren's syndrome) with broad experience encompassing B cell immunology, molecular immunology and genetic bases of disease. He completed his medical training at the University Hospital Center of Caen and Paris in France between 1999 and 2010. He is involved in a biomedical research project in Fabienne Mackay’s laboratory in order to complete a PhD. His project focuses on the role of B cell activating factor of the tumour necrosis factor (TNF) family (BAFF) and the innate immune system in the pathogenesis of the systemic lupus erythematosus. Another aim of this study is to characterize the role of BAFF and innate immunity markers in the increased frequency of lupus and auto-immune diseases observed in Australian Indigenous population.

Experience

  • 2011–present
    Senior Research Fellow, B lymphocyte, BAFF and Autoimmunity Laboratory, Monash University, Melbourne, Australia
  • 1999–2010
    Medical Training, University Hospital Center (CHU) of Caen and Paris, France

Education

  • 2011 
    University of Paris-Sud XI, France, Master in Sciences – Immunology, with high honours
  • 2010 
    University of Medicine, Paris and Lille, France, Degree in Polyarthritis and Autoimmune Disease
  • 2010 
    University of Medicine, Caen, France, Master in Clinical Research, with high honours
  • 2010 
    University of Medicine, Caen, France, M.D., Rheumatology board certified
  • 2009 
    University of Medicine, Nantes, France, Degree in interventional rheumatology
  • 2002 
    University of Medicine, Caen, France, Degree in Cytopathology and Immunopathology
  • 1999 
    Dumont D’Urville High School, Caen, France, High school degree in science, with honors

Publications

  • 2013
    Vincent FB et al. Clinical associations of serum interleukin-17 in systemic lupus erythematosus. , Arthritis Res Ther 2013
  • 2013
    Vincent et al. Antidrug antibodies (ADAb) to tumour necrosis factor (TNF)-specific neutralizing agents in chronic inflammatory diseases: a real issue, a clinical perspective., Ann Rheum Dis 2013;72:165-78
  • 2013
    Vincent FB et al. Focus on systemic lupus erythematosus in Indigenous Australians: toward a better understanding of autoimmune diseases., Intern Med J 2013;43:227-34
  • 2013
    Vincent FB et al. The BAFF/APRIL system: emerging functions beyond B cell biology and autoimmunity, Cytokine Growth Factor Rev 2013; 24:29-40
  • 2013
    Murielle M, Henri P, Vincent FB et al. Mesangial immunoglobulin (Ig)A glomerulonephritis in a patient with rheumatoid arthritis treated with abatacept., Joint Bone Spine 2013; doi:10.1016/j.jbspin.2013.05.003
  • 2013
    Figgett WA, Fairfax K, Vincent FB et al. TACI regulates Tindependent marginal zone B cell responses through innate activation-induced cell death., Immunity 2013
  • 2013
    Vincent FB et al. Association of serum B cell activating factor from the tumour necrosis factor family (BAFF) and a proliferation-inducing ligand (APRIL) with central nervous system and renal disease in systemic lupus erythematosus., Lupus 2013
  • 2012
    Vincent et al. BAFF and innate immunity: new therapeutic targets for systemic lupus erythematosus, Immunol Cell Biol 2012;90(3):293-303.

Grants and Contracts

  • 2010
    Role of BAFF/BLyS and the T-independent innate immune system in the Lupus pathogenesis
    Role:
    Funding Source:
    French Society of Rheumatology
  • 2010
    Role of BAFF/BLyS and the T-independent innate immune system in the Lupus pathogenesis
    Role:
    Funding Source:
    Gold Medal-University Hospital Center of Caen

Research Areas

  • Rheumatology And Arthritis (110322)
  • Immunology (1107)
  • Applied Immunology (Incl. Antibody Engineering, Xenotransplantation And T Cell Therapies) (110702)
  • Autoimmunity (110703)
  • Sports Medicine (110604)
  • Innate Immunity (110707)