Marc Zimmer teaches general chemistry, a first year seminar about bioluminescence and environmental chemistry. He has tried to make these courses relevant and interesting by introducing the most recent developments in general, medicinal and environmental chemistry in his classes.
Zimmer's book, Illuminating Disease: An Introduction to Green Fluorescent Proteins (Oxford University Press, 2015) uses fluorescent proteins as a thread to discuss modern diseases.
His research group is mainly interested in the structural and photophysical properties of Green Fluorescent Protein (GFP), a protein found in jellyfish that has found numerous uses as a marker in medicine, cell biology and molecular biology. This work is funded by the National Institute of Health and the Research Corporation. In 2008 he attended the Nobel Prize ceremony, the year that the chemistry award was presented to three scientists for their GFP research.