Research Fellow, University of Sydney

Tim is researching the role of neurocognition in psychiatric disorder and its treatment. He completed a PhD on antidepressants and genetic influences on brain activity, having implications for the treatment of mental disorders.

Tim completed a PhD within the Discipline of Psychiatry, Sydney Medical School, The University of Sydney, Sydney, Australia. Under the supervision of Professor Gin Malhi (University of Sydney) and associate supervision of Associate Professor Andrew Kemp (University of Sao Paolo; University of Sydney), Dr Pritha Das (University of Sydney), and Associate Professor Kim Felmingham (University of Tasmania), he researched the functional neuroimaging of emotion processing, antidepressant treatment, and genetics. Tim employed the imaging genetics and pharmacology paradigms in order to examine the initial and immediate changes in the emotion processing and regulation centres in the brain caused by antidepressants. Tim has undertaken training in fMRI experiment design and analysis.

Specialties

Neurocognition, Emotion, Psychiatric Disorder, Pharmacogenomics of Antidepressant Treatment, Neuroimaging, Psychophysiology, Affective Neuroscience, Psychopathology

Experience

  • 2014–present
    Postdoctoral research fellow, Discipline of Psychiatry, Sydney Medical School, The University of Sydney
  • 2011–2014
    PhD Candidate, Discipline of Psychiatry, Sydney Medical School, The University of Sydney

Education

  • 2014 
    The University of Sydney, PhD (Medicine) Discipline of Psychiatry, Sydney Medical School
  • 2012 
    ARCS Australia, Applied GCP Training for Investigational Sites and Sponsor Representatives
  • 2011 
    Harvard University, Visiting Fellowship in fMRI and SPM8 course
  • 2010 
    RMIT University, BAppSci(Psychology)(Hons)

Publications

  • 2014
    Outhred, T., Das, P., Dobson-Stone, C., Felmingham, K. L., Bryant, R. A., Nathan, P. J., Malhi, G. S., & Kemp, A. H. (2014). The impact of 5-HTTLPR on acute serotonin transporter blockade by escitalopram on emotion processing: Preliminary findings from a randomised, crossover fMRI study., Australian and New Zealand Journal of Psychiatr
  • 2014
    Kemp, A., Outhred, T., Saunders, S., Brunoni, A., Nathan, P., & Malhi, G. (2014). Impact of escitalopram on vagally mediated cardiovascular function in healthy participants: implications for understanding differential age-related, treatment emergent effects., Psychopharmacology
  • 2014
    Outhred, T., Das, P., Felmingham, K. L., Bryant, R. A., Nathan, P. J., Malhi, G. S., & Kemp, A. H. (2014). Impact of acute administration of escitalopram on the processing of emotional and neutral images: a randomized crossover fMRI study of healthy women., Journal of Psychiatry & Neuroscience
  • 2014
    Outhred, T., Kemp, A. H., & Malhi, G. S. (invited chapter). Physiological Correlates of Bipolar Disorder. In Kumari, V., Boutros, N., & Bob, P. (Eds.) , Current Topics in Behavioral Neurosciences: Psychophysiology in Psychiatry and Psychopharmacology,
  • 2013
    Hanson, Outhred, Brunoni, Malhi, & Kemp: The impact of escitalopram on vagally mediated cardiovascular function to stress and the moderating effects of vigorous physical activity: A randomized controlled treatment study in healthy participants., Frontiers in Physiology
  • 2013
    Outhred & Chester: international students, peer mentoring acculturation, wellbeing, Mentoring & Tutoring
  • 2013
    Braeken, M. A. K. A., Kemp, A. H., Outhred, T., Otte, R. A., Monsieur, G. J. Y. J., Jones, A., & Van den Bergh, B. R. H. (2013). Pregnant Mothers with Resolved Anxiety Disorders and Their Offspring Have Reduced Heart Rate Variability: Implications for the Health of Children., PloS One
  • 2013
    Outhred, Hawkshead, Wager, Das, Malhi, & Kemp: Acute Neural Effects of Selective Serotonin Reuptake Inhibitors versus Noradrenaline Reuptake Inhibitors on Emotion Processing: Implications for Differential Treatment Efficacy, Neuroscience & Biobehavioral Reviews
  • 2012
    Quintana, Guastella, Outhred, Hickie, & Kemp: Heart rate variability predicts emotion recognition: Direct evidence for a relationship between the autonomic nervous system and social cognition., International Journal of Psychophysiology
  • 2012
    Quinn et al. Keywords: BDNF and 5HTT polymorphisms, early life stress, Major Depressive Disorder, Australian and New Zealand Journal of Psychiatry
  • 2012
    Outhred, T., Das, P., Dobson-Stone, C., Griffiths, K., Felmingham, K. L., Bryant, R. A., et al. (2012, early view online). The functional epistasis of 5-HTTLPR and BDNF Val66Met on emotion processing: A preliminary study. , Brain and Behavior
  • 2012
    Quintana, D. S., Guastella, A. J., Outhred, T., Hickie, I. B., & Kemp, A. H. (2012, early view online). Heart rate variability predicts emotion recognition: Direct evidence for a relationship between the autonomic nervous system and social cognition. , International Journal of Psychophysiology
  • 2012
    Outhred, T., & Kemp, A. H. (2012). Impact of genetic epistasis on emotion and executive function: methodological issues and generalizability of findings, Genes, Brain, and Behavior
  • 2012
    Wells, R., Outhred, T., Heathers, J. A. J., Quintana, D. S., & Kemp, A. H. (2012). Matter Over Mind: A Randomised-Controlled Trial of Single-Session Biofeedback Training on Performance Anxiety and Heart Rate Variability in Musicians., PloS One
  • 2012
    Wells, R., Outhred, T., Heathers, J. A. J., Quintana, D. S., & Kemp, A. H. (2012). Matter Over Mind: A Randomised-Controlled Trial of Single-Session Biofeedback Training on Performance Anxiety and Heart Rate Variability in Musicians., PloS one
  • 2010
    Outhred & Chester. Keywords: class tutors, peer learning, Australasian Journal of Peer Learning Available from: http://ro.uow.edu.au/ajpl/vol3/iss1/3/,

Grants and Contracts

  • 2014
    SPARK Sydney
    Role:
    Co-Investigator
    Funding Source:
    UTS, University of Sydney, Stanford
  • 2014
    Ramsay Health
    Role:
    Investigator
    Funding Source:
    Ramsay Health and Kolling Institute
  • 2013
    Northern Clinical School Scholarship
    Role:
    PhD Candidate
    Funding Source:
    Sydney Medical School – Northern Clinical School, The University of Sydney
  • 2011
    Australian Postgraduate Award
    Role:
    PhD Candidate
    Funding Source:
    Australian Government

Research Areas

  • Psychology (1701)
  • Biological Psychology (Neuropsychology, Psychopharmacology, Physiological Psychology) (170101)
  • Psychiatry (Incl. Psychotherapy) (110319)
  • Neurogenetics (060410)
  • Neurosciences (1109)

Honours

Assoc MAPS BAppSci(Psychology)(Hons) PhD(Medicine)