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Fraunhofer IME

The Fraunhofer Institute for Molecular Biology and Applied Ecology IME is addressing different research areas in the field of applied life sciences, reaching from the molecular level towards complex ecosystems. The production and characterization of recombinant proteins using a large panel of different expression systems, including microbial systems, eukaryotic cells, as well as plants and plant suspension cells, is one of the IMEs main areas of expertise. The institute has more than 20 years of experience in the production of pharmaceutically relevant proteins of different types, covering vaccine candidates, cytokines, antibody fragments and full-length antibodies. These activities are being performed in the context of several public or industry-funded R&D projects, and the in house GMP-facility has been used for process development and production of clinical trial material in different expression systems, including E.coli, Pichia pastoris and transgenic tobacco plants.


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