Shutterstock/ktsdesign February 22, 2022 As New Zealand’s Omicron infections rise rapidly, genome surveillance is shifting gears David Welch, University of Auckland, Waipapa Taumata Rau; James Hadfield, Fred Hutchinson Cancer Center; Jemma Geoghegan, University of Otago; Joep de Ligt, ESR, and Michael Bunce, ESR Without genome sequencing, we would be blind to new variants of COVID-19. As Omicron surges in New Zealand, the sequencing focus is shifting to learning about what causes severe or long-term disease.