Developing drugs is typically the domain of large pharmaceutical companies. But here is an example of drug development for a rare pediatric brain cancer that was done in a university setting.
Drug trials should include people with more than one disease.
Nature doesn't always make the things we need so three Nobel Prize winners figured out how to fast-track evolution in the lab to create medicines, biofuels and industrial chemicals for modern life.
Trials for new Alzheimer's drugs have been failing a lot, lately. But it may be premature to abandon these drugs altogether.
Alzheimer's drug development tends to focus on protein aggregates in the brain. Perhaps that's why they've all failed.
Researchers who've created a kidney-on-a-chip explain why these kinds of devices are an improvement over traditional ways to test new drugs.
Thousands of animals are used for heart drug tests each year – but research shows that in silico developments are more accurate.
Medicinal chemists are tweaking a natural molecule that can be a deadly poison – a modified version might work as a nonhormonal male contraceptive.
Only around 10% of new drugs in development make it onto the market. A drug needs to go through animal trials, and then four phases of human trials to be deemed suitable for use in patients.
A randomised controlled trial is the best way to compare a new treatment with the standard treatment. And randomising trial participants is a core feature of the experiment.
3D bioprinting of living cells and materials may contribute to faster and cheaper ways to create effective new drugs - and even reduce animal testing.
Researchers are finding medical uses for some molecules in certain street drugs, but it's important to call the drugs by their real names. Here’s why that's important.
Australia has never been short of inventors, scientists aren't always at home in the ruthless world of commerce. But if they can be given a helping hand, it could help the entire economy.
News reports this week hailing a breakthrough in Alzheimer's research, saying a vaccine for the disease is a few years away, have raised hopes for many. But let's take a step back from the headlines.
Human guinea pigs? On the occasion of Rennes drama, an explanation of what the drug trials in France and how they are controlled.
Many venoms contain bioactive components that are so stable to the body's enzymes and selective of their biological target that they're increasingly being used as novel research tools.
Thalidomide was developed in an era of widespread enthusiasm – but little critical attention – for pharmaceutical therapies.
Thalidomide was marketed as a safe, sleep-inducing drug, but when taken during pregnancy it could cause severe birth defects.
Thalidomide caused thousands of spontaneous abortions and left more than 10,000 children severely disabled. What guarantee is there that the same thing can’t occur again today?
This project offers the tantalising possibility that plants containing drugs, such as agents to treat HIV, could be farmed on a small scale at low cost by communities that need them most.