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University of Chicago Pritzker School of Molecular Engineering

The Pritzker School of Molecular Engineering integrates science and engineering to address global challenges from the molecular level up. The school is the leading catalyst for the University of Chicago’s science community. The only school of its kind in the nation, PME is organized by research themes seeking to address some of humanity’s biggest challenges. The school offers an interdisciplinary education focused on: sustainability – including water and energy; immunoengineering – centered on health; and quantum – focused on driving quantum technologies such as quantum sensing, encryption, and computing. A fourth theme, STAGE, looks at the intersection of art and science. Faculty expertise spans eight scientific and engineering disciplines.


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Cette image de microscopie montre des cellules cancéreuses du pancréas en croissance (noyau en bleu, membranes en rouge). Min Yu/Eli et Edythe Broad Center for Regenerative Medicine and Stem Cell Research, USC / NIH / Flickr

Cancer : les thérapies de différenciation, ou comment faire revenir les cellules cancéreuses dans le droit chemin

De nombreuses tumeurs contiennent des cellules souches cancéreuses qui les aident à se développer et à échapper aux traitements. Une nouvelle piste tente de rendre ces cellules à nouveau normales.
This image shows pancreatic cancer cells (blue) growing, encased within membranes (red). Min Yu/Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC via NIH/Flickr

Triggering cancer cells to become normal cells – how stem cell therapies can provide new ways to stop tumors from spreading or growing back

Many tumors have cancer stem cells that help them grow and evade treatments. Differentiation therapy forces these cells to mature, stopping growth with less toxicity than traditional treatments.
Dendritic cells (green) produce cytokines like IL-12, which can train T cells (pink) to attack tumors. Victor Segura Ibarra and Rita Serda/National Cancer Institute via Flickr

‘Masked’ cancer drug stealthily trains immune system to kill tumors while sparing healthy tissues, reducing treatment side effects

One promising cancer treatment has been in the works for decades, but severe side effects have kept it out of the clinic. A reengineered version may offer a way to safely harness its potent effects.


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