‘Junk DNA’ can regulate cancer genes

Genetic sequences previously considered as “junk DNA” can regulate cancer genes, research has revealed.

Many cancers occur when genes that suppress tumours do not function properly, allowing the cancer to grow unchecked, but researchers discovered a new mechanism which can reactivate genes that have been switched off.

The research revealed multiple layers of complexity in the regulation of a tumour suppressor gene called PTEN.

Researchers hope switching the gene back on in cancer could make the tumours more sensitive to chemotherapy and prevent resistance to cancer drugs.

Read more at UNSW