Many Coles focuses on all adolescent issues, care for gender non-conforming youth, reproductive health and contraception. Research interests include pregnancy prevention, gender non-conforming youth, IUDs and contraceptive implants (LARC), and pregnancy assessment. She completed residency at Baystate Medical Center Children's Hospital, Springfield MA (2006) followed by a Fellowship in Adolescent Medicine, University of Rochester School of Medicine & Dentistry, Rochester NY (2009).