If only we had a few more recruits.
Trials into the effectiveness of drugs and treatments struggle to recruit enough participants, yet we rely on their results anyway.
Low cholesterol. Ka-ching! Glucose control. Ka-ching!
Pay-for-performance for doctors works brilliantly ... but only in theory.
So a tested medical intervention was found not to work. This should be just as big news as if it was found to be a success.
Why didn’t you hear about a recent big study on a new heart medication? Because the drug didn’t work. But that doesn't mean the study wasn't a success – it was.
Glass sculpture representation of Human Immunodeficiency Virus structure.
A new animal study has shown injections of antibodies might protect against HIV infection, albeit for only a limited time.
Do parents know enough about clinical trials to give informed consent?
Sick child image via www.shutterstock.com.
The dramatic improvements in survival for children with cancer depend on clinical trials, and these trials depend on parents understanding the possible risks and benefits involved.
Human guinea pigs? On the occasion of Rennes drama, an explanation of what the drug trials in France and how they are controlled.
Weighing the evidence.
Meta-analyses that combine many different studies are the gold standard for medical evidence. But they are only as good research they examine.
Events disturbingly similar to the thalidomide tragedy continue to occur.
Tighter regulations of medicines and devices have prevented countless deaths and disabilities. But regulation can't always protect us from harm.
Women would prefer a product that addresses multiple sexual and reproductive health risks at the same time.
Scientists are developing various products that can provide contraception and protection from sexually transmitted infections and HIV at the same time.
A new treatment for achondroplasia is helping to transform many kids’ lives.
A collaboration between research and industry has produced a promising new drug that could transform many childrens' lives. It's also a case study in innovation done right.
In most African countries, there is no oversight body for the pharmaceutical marketplace.
Africa's pharmaceutical industry has mushroomed in the last ten years. But its ability to keep pace with demand is being held back by a number of factors, including a shortage of specialists.
The concept of benefit sharing ensures that all who take part in research have sone form of gain from it.
Research should not only benefit the researchers. People who participate in research should also be compensated for the contributions.
When it comes to stem cells, the ways that informed consent has been obtained in the past are not sufficient and improvements are needed.
A health worker injects a woman with an Ebola vaccine during a trial in Monrovia, February 2 2015.
Was the Ebola vaccine 100% effective, or 100% lucky? The good money is on a percentage somewhere in between, but in truth, we will never know.
Tests by Shutterstock
We are engaged in one of the great struggles of human knowledge – to liberate clinical trial data.
The cheapest and most efficient means of conducting clinical trials lies in outsourcing to the ‘developing’ world.
On Human Experiments – As demand grows for newer and better drugs for an expanding range of conditions, so too does the need for clinical testing.
High costs are used to justify high drug prices.
Ever wonder how much it costs to develop a new drug? The Tufts Center for the Study of Drug Development estimates US$2.6 billion. But how accurate is this figure?
In the world of big data, the amount of paperwork for consent is old hat.
Paperwork by Shutterstock
In the world of big data and fast communication, why can't box ticking be made easier for researchers?
Clinical trials rely on statistics to show whether drugs are more effective than placebo pills. But how can we be certain?
Statistics are valuable tools for researchers - but may not be as reliable as we think. New research suggests the widely-used P value is inappropriate.
There are ways non-scientists can assess if the research underlying big claims about cancer cures stacks up.
Rafael Anderson Gonzales Mendoza/Flickr
Cancer is big news; we often hear of some kind of cure for some version of the illness. But whether it’s a “natural cure” or a promising molecule on its way to becoming a new medicine, there are ways non-scientists…