Aartjan te Velthuis is a group leader at the Department of Pathology of the University of Cambridge and a Henry Dale fellow of the Wellcome Trust and Royal Society.
He studies the replication of RNA viruses, focussing in particular on the enzyme that copies and transcribes the genetic material of the virus: the RNA polymerase.
Experience
2017–present
Group leader, University of Cambridge
2013–2017
Henry Wellcome Fellow, University of Oxford
2014–2017
Lecturer, Lincoln College Oxford
2012–2014
Junior Research Fellow, Lincoln College
2012–2013
Rubicon Fellow, University of Oxford
Education
2012
Leiden University, PhD cum laude/ Molecular Virology
2007
Leiden University, MSc cum laude/ Molecular Biology
Publications
2016
The role of the priming loop in influenza A virus RNA synthesis, Nature Microbiology
2014
Common and unique features of viral RNA dependent polymerases, Cellular and Molecular Life Sciences
2013
Uncoupling of influenza A virus transcription and replication through mutation of the unpaired adenosine in the vRNA promoter, Journal of Virology
2012
The SARS-coronavirus nsp7+nsp8 complex is a unique multimeric RNA polymerase capable of both de novo initiation and primer extension, Nucleic Acids Research
2010
Zn2+ inhibits Coronavirus and arterivirus RNA polymerase activity in vitro and zinc ionophores block nidovirus replication in cell culture, PloS Pathogens
2010
Quantitative guidelines for force calibration through spectral analysis of magnetic tweezers data, Biophysical Journal
2010
The RNA polymerase activity of SARS coronavirus is primer-dependent, Nucleic Acids Research