Aartjan te Velthuis

Wellcome Trust Fellow, University of Oxford

Aartjan te Velthuis is a group leader at the Department of Pathology of the University of Cambridge and a Henry Dale fellow of the Wellcome Trust and Royal Society.

He studies the replication of RNA viruses, focussing in particular on the enzyme that copies and transcribes the genetic material of the virus: the RNA polymerase.

Experience

  • 2017–present
    Group leader, University of Cambridge
  • 2013–2017
    Henry Wellcome Fellow, University of Oxford
  • 2014–2017
    Lecturer, Lincoln College Oxford
  • 2012–2014
    Junior Research Fellow, Lincoln College
  • 2012–2013
    Rubicon Fellow, University of Oxford

Education

  • 2012 
    Leiden University, PhD cum laude/ Molecular Virology
  • 2007 
    Leiden University, MSc cum laude/ Molecular Biology

Publications

  • 2016
    The role of the priming loop in influenza A virus RNA synthesis, Nature Microbiology
  • 2014
    Common and unique features of viral RNA dependent polymerases, Cellular and Molecular Life Sciences
  • 2013
    Uncoupling of influenza A virus transcription and replication through mutation of the unpaired adenosine in the vRNA promoter, Journal of Virology
  • 2012
    The SARS-coronavirus nsp7+nsp8 complex is a unique multimeric RNA polymerase capable of both de novo initiation and primer extension, Nucleic Acids Research
  • 2010
    Zn2+ inhibits Coronavirus and arterivirus RNA polymerase activity in vitro and zinc ionophores block nidovirus replication in cell culture, PloS Pathogens
  • 2010
    Quantitative guidelines for force calibration through spectral analysis of magnetic tweezers data, Biophysical Journal
  • 2010
    The RNA polymerase activity of SARS coronavirus is primer-dependent, Nucleic Acids Research

Grants and Contracts

  • 2017
    Henry Dale Fellowship
    Role:
    Principle investigator
    Funding Source:
    Wellcome Trust/Royal Society
  • 2012
    Rubicon Fellowship
    Role:
    Principle investigator
    Funding Source:
    Netherlands Organisation for Scientific Research
  • 2012
    Sir Henry Wellcome Fellowship
    Role:
    Principle investigator
    Funding Source:
    Wellcome Trust
  • 2007
    Toptalent scholarship
    Role:
    Principle investigator
    Funding Source:
    Netherlands Organisation for Scientific Research

Professional Memberships

  • Biochemical Society