We study gene and protein networks that affect cellular and organismal metabolism, ageing and disease.
Our interdisciplinary projects aim to identify drug targets and pharmacological interventions in metabolic syndromes and age-related diseases. We have experience in genome-wide genetic interactions, high-throughput cell based screens, phenomics, and transcriptomics. We analyse phenotype-genotype relationships, cross-talk of signalling pathways in senescence, stress, cellular metabolism and cytoarchitecture/topology.
Our research outputs impact on the fields of nutrition, diabetes, neurodegeneration, cancer and ageing.