David Wraith is an immunologist whose laboratory focuses on the use of fragments of antigens (peptides) for immunotherapy of allergic and autoimmune diseases. Antigen-specific immunotherapy aims to suppress the immunological drivers of these diseases but to do this specifically so that this only affects the cells causing disease and leaves the rest of the immune system fully capable of controlling cancers and infectious diseases. Our aim is to understand the mechanism by which this form of antigen-specific immunotherapy works and to demonstrate its broad application for the treatment of allergic and autoimmune diseases.