Dharani K Hapangama is Professor of Gynaecology and the deputy head of the department of Women’s & Children’s health, with an interest in translational endometrial research. She is a Consultant Gynaecologist at Liverpool Women’s Hospital and her research group works on normal regeneration of the human endometrium, endometrial epithelial stem cells and telomerase/telomere biology in the context of endometrial disease such as 'endometriosis', peri-conceptional pathology and 'endometrial cancer'.
The human endometrium is a major theme underpinning my research. My group focuses on the understanding of three dimensional organisation, function, and regeneration of the human endometrium in order to address major unmet clinical needs in gynaecology. We therefore centre our research on pathologies related to menstrual related symptoms, fertility/ early pregnancy and endometrial cancer.
Our research is funded by MRC, Wellbeing of Women’s, NIHR and North West Cancer Research.
Our research utilises a wide range of research methodology that has been established in our labs and supported by our expert national and international collaborators including; complex 3D in vitro tissue culturing; endometrial histology, immunohistochemistry, immuno-fluorescence, in situ hybridisation, laser capture micro-dissection, NMR, mass-spectroscopy and Raman spectroscopy, microarrays, RNA sequencing, imaging mass-spectroscopy as well as non-laboratory methods including systematic reviews and system biology.
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