Fabian V. Filipp is a professor for Systems Biology and Cancer Metabolism focused on the connection between epigenomic master regulators and their control over central metabolism as an opportunity for diagnosis and treatment of therapy-resistant cancers. He is author of “Systems biology analysis of mitogen activated protein kinase inhibitor resistance in malignant melanoma” and spearheads the cancer systems biology research group at the University of California Merced. Follow him on Twitter @cancersystembio and follow the conversation on Twitter with #myepigenome.
The combination of epigenetics, metabolomics and systems biology will bring about a revolution in biomedicine. Today’s routine use of metabolic multiplexing in the clinic will be enhanced by patient specific sequence; information and network models. The integration of systems biology networks into diagnostic interpretation of epigenetic and metabolomics readouts will naturally generate regimes for personalized medicine practice. In this sense, genomics, epigenomics, metabolomics and systems biology will fundamentally transform our approach to patient care, disease prevention, diagnostics, and therapy.