Dr. Ebersole received a BA in Biology from Temple University and a PhD in Microbiology from the University of Pittsburgh. He then did a postdoctoral fellowship in the Department of Immunology at The Forsyth Institute and remained on the faculty at Forsyth and Harvard School of Dental Medicine until 1985. From 1985-2000 he was a Professor in the Department of Periodontics and Microbiology at the University of Texas Health Science Center at San Antonio. From 2000-2017 he was the Alvin L. Morris Professor of Oral Health Research, Director of the Center for Oral Health Research and Associate Dean for Research in the College of Dentistry at the Univeristy of Kentucky. In 2017 he joined the School of Dental Medicine at the University of Nevada Las Vegas as Professor of Biomedical Sciences and Associate Dean for Research. In 1983 he received the IADR award for Basic Oral Science Research and in 2000 the IADR award for Basic Research in Periodontal Disease. In 2010 he received the Mentoring Award from the University of Kentucky Center for Clinical and Translational Sciences. In 2011-2012 he was the President of the American Association for Dental Research. In 2016 he was selected as a University Research Professor at the University of Kentucky. His CV contains over 300 publications, reviews and book chapters in the microbiology and immunology of oral diseases.
Dr. Ebersole’s laboratory focuses its research efforts on the immunobiology of oral infections. The research emphasizes in vitro, and in vivo studies of host-pathogen interactions using animal and human models of oral disease(s). He directed a major Center of Biomedical Research Excellence grant from the NIH supporting the Center for the Biologic Basis of Oral/Systemic Diseases for 13 years at the Univeristy of Kentucky. The COBRE center supported research projects extending over a range of oral-systemic disease studies, including HIV, pregnancy, gestational diabetes, cardiovascular disease, and inflammatory bowel disease, as well as genetic and environmental challenges that increase the risk of these diseases. The lab was also a part of a major NIDCR effort to identify and validate the potential for point-of-care salivary biomarkers as diagnostic tools for oral and systemic diseases. He served on the Internal Advisory Board of the UK Center for Clinical and Translational Sciences, and External Advisory Board for training grants at The Forsyth Institute, the University of Minnesota, the Ohio State University, and the University of Rochester. He serves on the Advisory Board of the UNLV Center for Biobehavioral Interdisciplinary Science, the Scientific Advisory Board of the Forsyth Institute, and as a Member of the Oral, Dental and Craniofacial Study Section (ODCS) of the Center for Scientific Review at the NIH.