Dr. Joshua Chou is a senior lecturer in the School of Biomedical Engineering (Faculty of Engineering and Information Technnology) at the University of Technology Sydney. Dr. Chou also serve as a core member of the Centre of Health Technology.
Dr. Chou’s laboratory works at the interface of biomaterials, cell mechanics, physics and cell biology, seeking to understand how physical properties and biological function affect each other in different cellular systems and diseases. These basic mechanical processes have profound effect in health (organ growth, heart/lung development) and diseases including cancer and osteoporosis.
Working with an international multidisciplinary team of engineers, biologists, and physicists from Harvard and MIT, the team seeks to understand physical properties of the living cell and their impact in health and disease.
By combining and applying the latest technology in mechanobiology, CRISPR/cas9 gene editing with single-cell sequencing, AI machine learning with super-resolution imaging, microfluidics and micro-contact patterning, Dr. Chou seek to understand disease mechanotransduction in hope of identifying therapeutic targets.