I am currently the Project Manager for the EpiTwin project. This project is a collaboration with the Beijing Genomics Institute (BGI) looking at the DNA obtained from whole blood for twins and comparing them with the patterns in their co-twin. Twin studies usually concentrate on the similarities between the twins, but for the purpose of this project, we will concentrate on the differences between twins. Initially the team will focus on obesity, diabetes, allergies, heart disease, osteoporosis and longevity.
Experience
2009–present
Quality Assurance Co-ordinator and Tutor for the Distance Learning MSc in Epidemiology, London School of Hygiene and Tropical Medicine
–present
ERC Project Manager, EpiTwin project, King's College London
2010–2010
Data Analyst , King's College London
2006–2009
Research Fellow for the Cochrane Heart Group , London School of Hygiene and Tropical Medicine
2005–2006
Postdoctoral researcher , Institute Pasteur de Lille
2001–2002
Clinical Scientist , LCG Biosciences
2000–2001
Grade A Clinical Scientist, The Tissue Typing Laboratory, Addenbrookes Hospital
London School of Hygiene and Tropical Medicine, Introductory Certificate in Learning & Teaching
2005
Peninsula Medical School, PhD - ‘The molecular genetics of circulating triglycerides in health and type 2 diabetes’
2005
Peninsula Medical School, Postgraduate Certificate of Clinical Research
1998
Univeristy of Manchester, MSc. – Biomedical and Forensic studies in Egyptology
1997
Nottingham Trent University, BSc 2ii (hons) – Combined Studies in Biology and Chemistry
Publications
2014
Differential Methylation of the TRPA1 Promoter In Pain Sensitivity , Nat Commun
2014
Hypermethylation in the ZBTB20 gene is associated with major depressive disorder, Genome Biology
2013
Statins for the primary prevention of cardiovascular disease, Cochrane Database of Systematic Reviews
2013
Biomarkers for type 2 diabetes and impaired fasting glucose using a non-targeted metabolomics approach, , Diabetes
2013
Dietary Advice for reducing cardiovascular risk, Cochrane Database of Systematic Reviews
2012
DNA methylation profiling in breast cancer discordant identical twins identifies DOK7 as novel epigenetic biomarker, Carcinogenesis
2011
Multiple risk factor interventions for primary prevention of coronary heart disease, Cochrane Database of Systematic Reviews
2011
Mendelian Randomization Studies do not Support a Role for Raised Circulating Triglyceride Levels influencing Type 2 Diabetes, Glucose Levels, or Insulin Resistance, Diabetes
2009
Metformin for obesity in children and adolescents: a systematic review, Diabetes Care
2008
Endocannabinoid receptor 1 gene variations increase risk for obesity and modulate body mass index in European populations, Human Molecular Genetics
2006
Triglyceride associated polymorphisms of the ApoA5 gene have very different allele frequencies in Pune, India compared to Europeans, BMC Medical Genetics
2006
Allelic Drop-out may occur with a primer binding site polymorphism for the commonly used RFLP assay for the -1131T>C polymorphism of the Apolipoprotein AV gene, Lipids Health Dis
2003
Genetic variants in Apolipoprotein AV alter triglyceride concentrations in pregnancy, Lipids Health Dis