Professor Tilley’s group undertakes research in the areas of cell biology and drug development related to the malaria parasite, Plasmodium falciparum.
She is particularly interested in the unusual protein trafficking pathways that the malaria parasite uses to display virulence proteins at the erythrocyte surface, and in understanding the molecular basis for the remarkable transformation that allows the malaria parasite to be transmitted from a human host to a mosquito vector.
Her lab also investigates the mechanisms of action of and resistance to the antimalarial drug, artemisinin, with a view to designing better antimalarial drugs.