Professor S.S. Vasan, who goes by his surname, is Honorary Professor of Health Sciences at the University of York (UK) and Honorary Professor of Medical and Health Sciences at the Edith Cowan University (Australia).
During 2019 to 2022, as CSIRO's COVID-19 science leader based at the Australian Centre for Disease Preparedness (ACDP), formerly the Australian Animal Health Laboratory, he led on research, development and preclinical evaluation of medical countermeasures for dangerous pathogens affecting humans and animals (zoonoses), especially those requiring high containment at biosafety level 3 or 4. The portfolio of projects he successfully initiated and led as Principal Investigator includes COVID-19 systems biology case control study in Victoria (CSIRO in partnership with Barwon Health and Deakin University), finding repurposed drugs for COVID-19 (MRFF), preclinical development of a warm vaccine and antibody therapy (Mynvax), and research on how the SARS-CoV-2 virus is mutating and its impact on vaccines and countermeasures (FDA). He led his ACDP project team to the Chairman's Medal 2020, the highest award bestowed by the national science agency of Australia, for critical preclinical evaluation studies on the Oxford-AZ (adenoviral) and Inovio (DNA) vaccines.
He was previously at the equivalent high containment facility in Porton Down, UK, and prior to that with Oxford University’s spin-out Oxitec as Head of Public Health working on arboviral diseases. Fellow of several professional bodies, he obtained his doctorate from Trinity College, Oxford, on a Rhodes Scholarship.
Experience
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2017–presentHonorary Professor of Health Sciences, University of York
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2023–presentHonorary Professor of Medical and Health Sciences, Edith Cowan University
Education
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1998Trinity College, Oxford, Doctor of Philosophy
Publications
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2022Tracking co-occurrence of N501Y, P681R, and other key mutations in SARS-CoV-2 spike for surveillance, https://www.mdpi.com/2813-0227/2/3/14/htm
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2022Advances and gaps in SARS-CoV-2 infection models, https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1010161
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2022Evaluation of host protein biomarkers by ELISA from whole lysed peripheral blood for development of diagnostic tests for active tuberculosis, https://www.frontiersin.org/articles/10.3389/fimmu.2022.854327/abstract
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2022Highly thermotolerant SARS-CoV-2 vaccine elicits neutralising antibodies against Delta and Omicron in mice, https://www.mdpi.com/1999-4915/14/4/800/htm
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2022Characterisation and natural progression of SARS-CoV-2 infection in ferrets, https://www.nature.com/articles/s41598-022-08431-6
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2022At least three doses of leading vaccines essential for neutralisation of SARS-CoV-2 Omicron variant (Frontiers in Immunology, in press, doi: 10.3389/fimmu.2022.883612), https://doi.org/10.1101/2022.02.20.22271237
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2022Systematic down-selection of repurposed drug candidates for COVID-19, https://www.mdpi.com/1422-0067/23/19/11851/htm
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2022Use of human lung tissue models for screening of drugs against SARS-CoV-2 infection, https://www.mdpi.com/1999-4915/14/11/2417
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2022CoviRx: A user-friendly interface for systematic down-selection of repurposed drug candidates for COVID-19, https://www.mdpi.com/2306-5729/7/11/164/htm
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2022A time-series metabolomic analysis of SARS-CoV-2 infection in a ferret model, https://www.mdpi.com/2218-1989/12/11/1151
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2021Live virus neutralisation of the 501Y.V1 and 501Y.V2 SARS-CoV-2 variants following INO-4800 vaccination of ferrets, https://www.frontiersin.org/articles/10.3389/fimmu.2021.694857
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2021ChAdOx1 nCoV-19 (AZD1222) vaccine candidate significantly reduces SARS-CoV-2 shedding in ferrets, https://www.nature.com/articles/s41541-021-00315-6
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2021Unhelmeted two-wheeler riders in India, https://www.nmji.in/preprintarticle.asp?id=321683
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2021Altered microRNA expression in COVID-19 patients enables identification of SARS-CoV-2 infection, https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1009759
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2021But Mouse, you are not alone: On some severe acute respiratory syndrome coronavirus 2 variants infecting mice, http://dx.doi.org/10.1093/ilar/ilab031
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2021Immunogenicity and protective efficacy of a highly thermotolerant, trimeric SARS-CoV-2 receptor binding domain derivative, https://pubs.acs.org/doi/10.1021/acsinfecdis.1c00276
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2021A stabilized, monomeric, Receptor Binding Domain elicits high-titer neutralizing antibodies against all SARS-CoV-2 variants of concern, https://www.frontiersin.org/articles/10.3389/fimmu.2021.765211/
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2021In vitro characterisation of SARS‐CoV‐2 and susceptibility of domestic ferrets (Mustela putorius furo), https://onlinelibrary.wiley.com/doi/abs/10.1111/tbed.13978
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2021Metabolic profiling from an asymptomatic ferret model of SARS-CoV-2 infection, https://doi.org/10.3390/metabo11050327
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2021Type I hypersensitivity in ferrets following exposure to SARS-CoV-2 inoculum: lessons learned, https://academic.oup.com/ilarjournal/advance-article/doi/10.1093/ilar/ilab019/6299200
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2020Animal models for COVID-19, https://www.nature.com/articles/s41586-020-2787-6
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2020Decay of SARS-CoV-2 and surrogate murine hepatitis virus RNA in untreated wastewater to inform application in wastewater-based epidemiology, https://doi.org/10.1016/j.envres.2020.110092
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2020Validation of differentially expressed immune biomarkers in latent and active tuberculosis by real-time PCR, https://www.frontiersin.org/articles/10.3389/fimmu.2020.612564/
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2020Interoperable medical data: the missing link for understanding COVID‐19, https://onlinelibrary.wiley.com/doi/10.1111/tbed.13892
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2020Experimental and in silico evidence suggests vaccines are unlikely to be affected by D614G mutation in SARS-CoV-2 spike protein, https://www.nature.com/articles/s41541-020-00246-8
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2020Supporting pandemic response using genomics and bioinformatics: A case study on the emergent SARS‐CoV‐2 outbreak, https://onlinelibrary.wiley.com/doi/10.1111/tbed.13588
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