Simon Capewell qualified at Newcastle University. He subsequently worked in Edinburgh, Cardiff, Oxford, and Glasgow in respiratory and cardiovascular medicine, then in public health from 1990. Since moving to Liverpool in 1999, his research has focussed on the epidemiology, modelling and prevention of cardiovascular disease (CVD). He actively contributes to the Heart of Mersey CVD primary prevention programme, and to developing CVD prevention policy in the UK and beyond.
Simon's current programmes include cardiovascular disease (CVD) epidemiology; modelling CVD trends in different countries; and the inequalities associated with CVD prevention by medications and by policy interventions. Simon and colleagues have been developing CVD models to try and explain why CVD mortality rates have recently fallen substantially in the UK and many other countries. Specifically, why some two-thirds of this mortality fall might be due to risk factor improvements (as opposed to just one third from modern cardiological treatments).