Sinead Delany-Moretlwe, MBBCh PhD DTM&H is Associate Professor and Director: Research at Wits RHI. A South African-born medical doctor, she has fifteen years’ experience in sexual and reproductive health and HIV prevention research and is recognized for her expertise in the prevention of HIV and other viral sexually transmitted infections (including HSV-2 and HPV), particularly for young women. She was an investigator on several ground-breaking phase III trials to evaluate herpes treatment for HIV prevention, and also has extensive microbicide research experience. She worked as an investigator on several phase II and III trials of novel microbicides, and most recently was the Medical Director on the FACTS 001 phase III licensure trial of 1% tenofovir gel. She has also worked on studies of novel diagnostics for cervical cancer screening, and vaccines. Currently she is a principal investigator on three PrEP demonstration projects for adolescent girls and young women, with a particular focus on evaluating interventions that may address the social and structural barriers to PrEP use in young women. She is also technical lead on a PEPFAR Innovations award to strengthen testing and linkage to treatment and prevention in adolescents. Prof Delany-Moretlwe has currently serves on the South African National Aids Council (SANAC) prevention technical task team, and has served as a technical advisor on national and global committees that address the prevention of HIV and other STIs, as well as several Data Safety and Monitoring Committees. She is an author on > 90 scientific articles and was the recipient of an Overseas Research Scholarship Award, a National Research Foundation Thuthuka Award and an EDCTP Senior Fellowship.