Dr Griffin obtained a 1st class degree in Natural Sciences from the University of Cambridge in 1997. He remained in Cambridge to undertake a PhD in the Department of Medicine with Prof Andrew Lever, where he identified the major RNA encapsidation signal for human immunodeficiency virus type 2 (HIV-2) and developed the first vector gene delivery system based on the virus.
In 2001 Dr Griffin moved to the Faculty of Biological Sciences at the University of Leeds as a post-doctoral fellow with Profs David Rowlands and Mark Harris. Here, he discovered the function of the p7 ion channel encoded by hepatitis C virus (HCV), which became a major research interest and won him the UK Society of General Microbiology Sir Howard Dalton Prize in 2003.
Dr Griffin began his independent academic career in 2007 with the award of an MRC New Investigator grant, continuing his interests in virus-coded ion channels and expanding research on HCV. In 2010, he moved to the former Leeds Institute of Molecular Medicine within the Faculty of Medicine and Health as a Senior Fellow and Group leader, exploring the link between HCV infection and liver cancer. As an Associate Professor in Viral Oncology, Dr Griffin has translational interests in antiviral and anti-tumour therapies, well established clinical collaborations, and ongoing research into the mechanisms underpinning virus-mediated transformation.