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Articles on Vaccine development

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Research technician Leon McFarlane handles a blood sample from a volunteer in the laboratory at Imperial College in London, where a COVID-19 vaccine is under development, on July 30, 2020. (AP Photo/Kirsty Wigglesworth)

Canada’s ‘me first’ COVID-19 vaccine strategy may come at the cost of global health

With $1 billion in advance purchase agreements for COVID-19 vaccines, Canada has joined the vaccine nationalists: rich countries buying up more than half the global short-term supply of vaccine.
A lab technician holds a vial of a COVID-19 vaccine candidate during testing at the Chula Vaccine Research Center, run by Chulalongkorn University in Bangkok, Thailand on May 25, 2020. (AP Photo/Sakchai Lalit)

Explainer: How clinical trials test COVID-19 vaccines

Will a vaccine for COVID-19 be safe? Animal testing, human clinical trials and post-approval surveillance give us good grounds to believe that a future approved vaccine will work and be safe.
A scientist holding a coronavirus vaccine at the Nikolai Gamaleya National Center of Epidemiology and Microbiology in Moscow, Russia. Alexander Zemlianichenko Jr/Russian Direct Investment Fund/AP/AAP

Russia’s coronavirus vaccine hasn’t been fully tested. Doling it out risks side effects and false protection

If the vaccine does not protect individuals from infection, those who have been vaccinated could falsely believe they are protected.
Vaccinologists have not focused their research on tailoring vaccines to induce robust immune responses in the elderly. (Shutterstock)

Why vaccines are less effective in the elderly, and what it means for COVID-19

Immunosenescence — the decline of immune system function with age — means that vaccines are not as effective in older adults, the demographic most susceptible to many diseases, including COVID-19.
A general view during the country’s first human clinical trial for a potential COVID-19 vaccine in Soweto, South Africa. Felix Dlangamandla/Beeld/Gallo Images via Getty Images

COVID-19 vaccine trial in South Africa: everything you need to know

There isn’t enough clinical research being done in Africa. This has had a lot of repercussions in terms of the timing when interventions become available and effective in high income countries.
The scope and length of vaccine testing experiments usually mean decade-long timelines for development. (Pixabay)

Fast COVID-19 vaccine timelines are unrealistic and put the integrity of scientists at risk

It usually takes 10 years for a new vaccine to complete clinical trials, but we’ve been promised a COVID-19 vaccine in 12 to 18 months. Even if such fast-tracked development is possible, is it wise?

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