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Articles on Cancer resistance

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Advances in radiotherapy involve combining new technologies with clinical expertise. Kateryna Kon/Science Photo Library via Getty Images

Radiation therapy takes advantage of cancer’s poor DNA repair abilities – an oncologist and physicist explain how

Radiotherapy takes many forms: from directing powerful high-energy beams toward specific areas of the body to placing radioactive seeds right next to tumors.
Most tumors are made up of many different kinds of cancer cells, as shown in this pancreatic cancer sample from a mouse. Ravikanth Maddipati/Abramson Cancer Center at the University of Pennsylvania via National Cancer Institute

Every cancer is unique – why different cancers require different treatments, and how evolution drives drug resistance

There is no one-size-fits-all approach to treating cancer. Understanding how cancer cells evolve could help researchers develop more effective drugs.
Collaborations between mathematicians, cancer biologists and clinical oncologists enable both rapid cost-effective testing of cancer drug combinations, and deeper understanding of cancer drug resistance. (Shutterstock)

How mathematics is helping to fight cancer

Cancer is the second leading cause of death globally. Mathematicians have joined the fight, developing models to both test cancer drug combinations and understand chemotherapy drug resistance.
Elephants express many extra genes derived from the critical tumour suppressor gene TP53. Stephen Tan/Flickr

What elephants teach us about cancer prevention

Elephants naturally avoid cancer after 55 million years of evolution. Scientists are studying if they can extract lessons that could help people.

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