New strategy helps build synthetic organs from scratch. This enabled the researchers to grow functioning liver tissue in the lab that could be transplanted into mice with liver disease.
Currently, stem cell based treatments are still mostly experimental, and while some results are encouraging, several clinical trials have failed.
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Stem cells show much promise, both for testing drugs and for treating disease. But the hype around them has been dangerous, as most treatments are in very experimental stages and can cause harm.
Lab-grown organs may not be so easy to transplant into a patient.
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Tobias Deuse, University of California, San Francisco
The idea behind regenerative medicine is that the patient is both the donor and recipient of healthy tissue grown from stem cells. But sometimes the transplanted cells are rejected. Now we know why.
Marius Wernig, Thomas C. Südhof and their colleagues created these “Induced neuronal (iN) cells” from adult human blood cells.
Marius Wernig
Figuring out what causes diseases like autism, schizophrenia and depression is tricky. Now Stanford University researchers are turning blood into brain cells to study these diseases in a dish.