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Articles on Off-label prescribing

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Research suggests that about 20% of all prescriptions are administered “off-label.” Hafakot/iStock via Getty Images Plus

Off-label’ use is common in medicine – a bioethicist and legal philosopher explain why the COVID-19 vaccines are different

The CDC’s COVID-19 vaccine provider agreement prohibits health care professionals from administering the vaccines in people for whom they are not yet authorized or approved. But this departs from longstanding norms.
As public figures and some in the media touted hydroxychloroquine, prescriptions skyrocketed. Grace Cary / Moment via Getty Images

When Trump pushed hydroxychloroquine to treat COVID-19, hundreds of thousands of prescriptions followed despite little evidence that it worked

When news reports tout a drug, people get interested, even if the benefits are unproven. Patient hopes, requests and demands can easily turn into real prescriptions in their doctor’s office.

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