Following the controversial births of the first gene-edited babies, a major focus of the Third International Summit on Human Genome Editing was responsible use of CRISPR.
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Articles on Sickle cell anaemia
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Molecular research is expensive, but worth it because of the burden of disease that it could relieve.
Life-saving blood is needed for everything from treating cancers and chronic conditions to helping trauma victims. But blood donations have dropped to crisis levels during the pandemic.
Evolutionary medicine uses our ancestral history to explain disease prevalence and inform care for conditions like Type 2 diabetes. It also challenges the bio-ethnocentrism of western medicine.
Today, human populations carry heavy genetic marks from the war with malaria. And it is the red blood cell (erythrocyte) that mostly bears the scars.
Once genetic lesions for diseases such as cystic fibrosis and haemophilia were identified, the idea of replacing or correcting defective genes grew into what we now call “gene therapy”.
Cystic fibrosis is the most common genetic disease among Caucasians. Now scientists believe they have discovered the origin of this often lethal genetic mutation and how it spread throughout Europe.
New research shows just 1% of E. coli bacteria’s genetic mutations are lethal.
Gene therapy is allowing us to switch on natural beneficial mutations to counteract the effects of negative mutations in diseases such as sickle cell anaemia.
Every year, 300,000 children are born with sickle-cell disease, primarily in Africa and India. It is a genetic disorder that causes some blood cells to become abnormally shaped. The result is that those…
Genetic mutations that affect our blood cells’ haemoglobin are the most common of all mutations. It has been estimated that around 5% of the world’s population carry a defective globin gene. Haemoglobin…
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Merlin Crossley is a Friend of The Conversation.Deputy Vice-Chancellor Academic Quality and Professor of Molecular Biology, UNSW Sydney
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Division Head, Population Health and Immunity, Walter and Eliza Hall Institute
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Postdoctoral Fellow, Harvard University
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Professor and Eugene M. Isenberg Chair in Integrative Studies, UMass Amherst
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Professor - Applied Evolutionary Ecology, Laurentian University
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Senior Lecturer in Medical Genetics, Kingston University
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Professor of Pediatrics and Population Health Sciences, University of Wisconsin-Madison
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Interim Dean/Professor-College of Science, Rochester Institute of Technology
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PhD Candidate, Biomolecular Sciences, Laurentian University
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Graduate Student - Department of Psychology, Laurentian University
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Senior lecturer in Molecular Pathology and Microbial Genetics, University of Nigeria
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Professor of Bioinformatics, Rochester Institute of Technology
