Scientist Doris Taylor explains how she and her team are creating bioengineered human hearts in their lab with the goal of one day eliminating the need for heart transplants.
A Sudanese man who testified to selling a kidney to traffickers in 2017.
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Biased algorithms in health care can lead to inaccurate diagnoses and delayed treatment. Deciding which variables to include to achieve fair health outcomes depends on how you approach fairness.
Tylenol overdose is one of the leading causes of liver injury requiring liver transplantation.
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Liver transplant waitlists can range from 30 days to over five years. Developing treatments that spur liver regeneration could help reduce demand for scarce organs.
From next year, uterus transplants are being trialled in Australia. But it’s likely to be a while before they becomes mainstream clinical treatment.
A limited supply of donor organs, paired with a massive demand for transplants, has fuelled the global organ trafficking industry, which exploits poor, underprivileged and persecuted members of society as a source of organs to be purchased by wealthy transplant tourists.
(AP Photo/Ebrahim Noroozi)
China’s industrial-scale organ trafficking practice has been executing prisoners of conscience and using their organs for transplantation for decades. This is known as forced organ harvesting.
Stem cell transplants involve completely eliminating and then replacing the immune system of a patient, often by transplanting the bone marrow.
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Patients with blood cancer undergoing stem cell transplantation have a high risk of complications. The bacteria in their gut, however, can help their immune system recover and fight infections.
Cross-species transplants require us to examine the relationships between humans and animals.
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The heart used in the first pig-human transplant was infected with a pig virus. This reveals that using other species as organ donors may not provide a solution for organ shortages.
Xenotransplantation has made significant strides over the past few decades.
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Recent successes putting genetically modified pig organs into people have brought xenotransplantation back into the spotlight.
Xenotransplantation is the transplanting of cells, tissues or organs from animals to humans. Pre-clinical trials of organ transplant from pigs have addressed some of the technical barriers.
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New developments in organ transplants from animals show promise. However, there has been no public engagement about a potential risk. It may streamline a pathway to humans for new zoonotic diseases.
Surgeon at the University of Maryland Medical Center in Baltimore, holding up the genetically modified heart that would be transplanted into David Bennett.
University of Maryland School of Medicine
David Bennett owes a debt of gratitude, not only to the surgeon’s who saved his life but to Peter Medawar, the person who discovered why organs are rejected.
Cancer and organ transplant patients, people with untreated HIV and people with other immunodeficiencies are at high risk of severe COVID-19 infection.
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Printing organs could reduce the need for human donor organs. And 3D printed organs using a patient’s own cells would increase successful organ transplants by reducing the risk of rejection.
Deemed consent, or ‘opt-in,’ organ donation is a significant departure from the practices of health-care consent in Canada.
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Deemed consent organ donation means that everyone is assumed to be an organ donor unless they opt out, but assuming consent raises some ethical issues.
A cross section of lab-grown human liver tissue. The green shows the network of blood vessels.
Velazquez et al. Cell Systems
New strategy helps build synthetic organs from scratch. This enabled the researchers to grow functioning liver tissue in the lab that could be transplanted into mice with liver disease.
The Biden administration can make significant changes in health care for Americans.
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From expanding children’s coverage to reducing surprise bills, Biden and lawmakers may be able to broaden health care access.
The airline industry has been cancelling routes because of the traffic drop-off during the pandemic. That has an impact on organ transplants.
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Tinglong Dai, Johns Hopkins University School of Nursing; Guihua Wang, University of Texas at Dallas et Ronghuo Zheng, The University of Texas at Austin
As policymakers weigh financial aid for the airline industry, they have an opportunity to help make the US organ transplantation system more equitable at the same time.
Eighty-five per cent of Ontarians support organ donation, but only one-third have opted in under the current system.
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Thousands of Canadians are on waiting lists for life-saving organ transplants. An opt-out organ donor system, like the one Nova Scotia is implementing, could reduce avoidable deaths and suffering.
Visiting Professor in Biomedical Ethics, Murdoch Children's Research Institute; Distinguished Visiting Professor in Law, University of Melbourne; Uehiro Chair in Practical Ethics, University of Oxford
Professor of Bioethics & Medicine, Sydney Health Ethics, Haematologist/BMT Physician, Royal North Shore Hospital and Director, Praxis Australia, University of Sydney