Alison Grant is member of Faculty at Africa Health Research Institute (AHRI) and a Professor of International Health at the London School of Hygiene and Tropical Medicine (LSHTM). She initially trained as a physician specialising in infectious and tropical diseases and HIV medicine, and continues to see patients at the Mortimer Market centre HIV clinic in London. Prof Grant also holds a PhD in epidemiology. Her main research interest is improving care for HIV-positive people in resource-limited settings, and preventing tuberculosis (TB). Since 1997, Prof Grant’s research has primarily been based in South Africa where her work has focussed on the development and evaluation of interventions to reduce HIV-related illness and death, and particularly HIV-related TB. Major projects she has led and collaborated on include a cluster-randomised trial investigating a point-of-care TB test and treat algorithm for people with advanced HIV disease; evaluation of South African national roll-out of Xpert MTB/RIF, a new TB diagnostic test replacing smear microscopy; investigation of how best to use Xpert MTB/RIF among people attending clinics for HIV care; linkage to care after a rifampicin-resistant Xpert MTB/RIF result and a trial comparing a single round of weekly isoniazid/rifapentine to periodic treatment.