Our group’s focus is understanding how RNA viruses replicate at the molecular and biochemical levels in order to develop novel strategies for the prevention and treatment of RNA virus diseases. We are also interested in developing novel virus-based tools that can be used by the wider scientific community. We use a wide range of tools (classical virology, molecular biology, cell biology, biochemistry, engineering, computational biology, etc.) to understand how these important human pathogens replicate and use this information to help improve human and animal health.