Gabriel Reboux

Experience

• 2000–2024
  Associate research scientist, University hospital of Besançon (France)

Education

• 2006 
  Université de Franche-Comté. Faculté de Médecine et de Pharmacie, • Habilitation à Diriger des Recherches
• 2000 
  Ecole Pratique des Hautes Etudes et de l'Université de Franche-Comté , Doctorat Sciences de la Vie et de la Terre et Sciences de la Vie et de la Santé
• 1997 
  Ecole Pratique des Hautes Etudes- La Sorbone, • Diplôme de l’Ecole Pratique des Hautes Etudes
• 1996 
  Ecole Pratique des Hautes Etudes- La Sorbone, • Certificat de Capacité à la Recherche de l’Ecole Pratique des Hautes Etudes

Publications

• 2023
  Development of a cockroach (Blattella germanica) qPCR for the objective measurement of exposure at home , Stoten
• 2023
  Whispers of change in preschool asthma phenotypes: Findings in the French ELFE cohort, Resp med
• 2022
  Investigation of the value of precipitins in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) patients with a positive marker for Aspergillus species, Med Mycol
• 2022
  Indoor fungi threshold levels Chapitre 10, Elsevier
• 2022
  Bird fancier’s lung serodiagnosis by automated r-IgLL1 ELISA, J Immunol Meth
• 2021
  One-year latter: the effect of change Azole treated bulbs for organic tulips bulbs in hospital environment on the azole-resistant Aspergillus fumigatus rate, Med Mycol
• 2021
  Impact of domestic mould exposure on Aspergillus biomarkers and lung function in patients with chronic obstructive pulmonary disease., Environ Res
• 2021
  Factors associated with Pneumocystis colonisation and circulating genotypes in COPD patients with acute exacerbation or at stable state and their homes, Med Mycol
• 2021
  Occupational hypersensitivity pneumonitis and organic dust toxic syndrome. Chapitre 24, . Asthma et the workplace 5th Ed. Bernstein et Malo eds
• 2021
  t study using recombinant antigens r-PROE and r-IGLL1 for the serodiagnosis of feather duvet lung, Archivos de Broncopneumologia
• 2021
  Molecular epidemiology of azole-resistant Aspergillus fumigatus in sawmills of Eastern France by microsatellite genotyping, Journal of Fungi (Basel)
• 2020
  Usefulness of bronchoalveolar lavage in a French pediatric cohort with hypersensitivity pneumonitis, Pediatr Pulmonol
• 2020
  Indoor Microbiome: Quantification of Exposure and Association with Geographical Location, Meteorological Factors, and Land Use in France, Microorganisms
• 2020
  Azole-resistant Aspergillus fumigatus in the hospital: Surveillance from flower beds to corridors, Am J Infect Control
• 2020
  Effects of plant features on symptoms and airway inflammation in compost workers followed over 18 months, Arch Environ Occup Health
• 2020
  Studying smoking benefit in farmer’s lung to understand Covid-19, Occ Med (London)
• 2019
  Azole-resistant Aspergillus fumigatus : a global phenomenon originating in the environment ? , Med Mal Inf
• 2019
  Microbial exposure to dairy farmers' dwellings and COPD occurrence, Int J Environ Health Res
• 2019
  Survey of 1012 moldy housing by culture fungal analysis: threshold proposal for asthmatic patient management, Indoor air
• 2019
  Hypersensitivity pneumonitis in a cystic fibrosis patient, Occ Med (London)
• 2019
  Identifying indoor air Penicillium species: a challenge for allergic patientsl, J Med Microbiol
• 2019
  Hypersensitivity pneumonitis: a new strategie for serodiagnosis and environmental survey, Resp med
• 2019
  Storage mites concentrations are underestimated compared to house dust mites concentrations, Exp Appl Acarol
• 2018
  Fungal contamination of wind instruments: immunological and clinical consequences on musicians, Stoten
• 2018
  Hypersensitivity pneumonitis caused by chinchilla, J Investigational allergol & clin immunol
• 2018
  Aspergillus fumigatus azole-resistance in COPD patients and their homes: high prevalence and frequent coexistence of sensitive and resistant isolates, Indoor air
• 2018
  Screening of common proteins to bird droopings related to Bird Fancier’s Lung, J Investig Allergol Clin Immunol
• 2018
  Mould exposure in indoor environments: The French ANSES recommendations to reinforce measures for preventing mould growth and the impact on human health, Indoor air
• 2018
  Wheezing phenotypes and risk factors in early life: The ELFE cohort, PlosOne
• 2018
  Exposure to field versus storage wheat dust: different consequences on respiratory symptoms and immune response among grain workers, Int Arch Occup Environ Health
• 2018
  Determination of azole fungal residues in soils and detection of Aspergillus fumigatus resistant strains in market gardens of Eastern France, Environ Sci Pollut Res Int
• 2018
  Lack of evidence of IgE allergic sensitisation from working with lactic acid bacteria in the dairy foods industry, J of Dairy research
• 2017
  Usefulness of a la carte antigens for bird fancier’s lung serodiagnosis: total dropping extract and/or dropping’s microflora antigens , J Med Microbiol
• 2017
  DNA metabarcoding to assess indoor fungal contamination: Electrostatic dust collectors and Illumina sequencing, J Microbiol Methods
• 2017
  Fungal peptides from pneumonitis hypersensitivity etiologic agents are able to induce specific cellular immune response, J Immunol Methods
• 2017
  Fungal aerocontamination exposure risk for patients in three successive locations of a Pediatric Hematology Department: influence of air equipment and building structure on air quality, Am J Infect Control
• 2017
  Saprolegnia parasitica qPCR quantification in river water: From massive fish kills to tap drinking water, Int J Environ Health Res
• 2017
  Azole-resistant Aspergillus fumigatus in sawmills of Eastern France, J Appl Microb
• 2017
  An immunoproteomic approach revealed antigenic proteins enhancing serodiagnosis performance of Bird fancier’s lung, J Immunol Methods
• 2016
  Common peptides epitopes induce cross-reactivity in Hypersensitivity pneumonitis serodiagnosis, JACI
• 2016
  Assessment of pets (cats and dogs) in home using electrostatic dust collectors and QPCR: new tool to evaluate exposure and risk of allergies, Int J Environ Health Res
• 2016
  Positive fungal quantitative PCR and Th17 cytokine detection in bronchoalveolar lavage fluids: complementary biomarkers of hypersensitivity pneumonitis? , J Immunol Methods
• 2016
  Microbiological consequences of indoor composting, Indoor air
• 2016
  Replies to “Is the home environment an important factor in the occurrence of fungal events in cystic fibrosis?”, J Cyst Fibro
• 2016
  Hypersensitivity pneumonitis in a beautician, Am J Med Ind
• 2016
  Sinus aspergillosis due to an azole-resistant Aspergillus fumigatus strain carrying the TR34/L98H mutation in immunocompetent host, Infect Dis (Lond)
• 2016
  identification of antigenic proteins from Lichtheimia corymbifera for Farmer’s lung disease diagnosis, PlosOne
• 2015
  New Commercially Available IgG Kits and Time-Resolved Fluorometric IgE Assay for Diagnosis of Allergic Bronchopulmonary Aspergillosis in Patients with Cystic Fibrosis, J Cyst Fibro
• 2015
  Respiratory health effects of fifteen years of improved collective protection in a wheat processing worker population, Ann Envir Agric Med
• 2015
  Microbiological characterization of 3193 French dwellings of Elfe cohort children, Stoten
• 2015
  Evaluation of mold exposure in cystic fibrosis patients’ dwellings and allergic bronchopulmonary risk, J Cyst Fibro
• 2015
  Western blot as a tool fort the serodiagnosis of farmer’s lung disease diagnosis: validation with Lichtheimia corymbifera proteins extracts, J Med Microbiol
• 2015
  Working with argan cake: a new etiology for hypersensitivity pneumonitis, BMC Pulm Med
• 2014
  Azole-resistant TR34/L98H Aspergillus fumigatus in both fungicide-sprayed field and lung of a hematopoietic stem cell transplant recipient with invasive aspergillosis, J Clin Microbiol
• 2014
  Immunoreactive proteins of Saccharopolyspora rectivirgula for farmer's lung serodiagnosis, Proteomics Clin Appl
• 2014
  Occupational hypersensitivity pneumonitis in a baker: a new cause, Chest
• 2014
  qPCR standard operating procedure for measuring Microorganisms in dust from dwellings in large cohort study, Stoten
• 2014
  Evaluation of fungal risk for immunocompromised patients alternatively hospitalized in haematology ICU and at home, Indoor air
• 2014
  External validationof Recombinant antigens for serodiagnosis of Machine Operator’s lung, Am J Ind Med
• 2014
  Immunogenic proteins specific to different bird species in Bird Fancier’s Lung, J Toxicol Environ Health, Part A
• 2014
  A ten-year survey of general hospital corridors fungal aero-contamination: reliable sentinel to predict fungal exposure risk? , J Hosp Inf
• 2014
  Immunoproteomics for serological diagnosis of hypersensitivity pneumonitis caused by environmental microorganisms, Curr Protein Pept Sc
• 2014
  Indoor fungal contamination: health risks and measurement methods in hospitals, home and workplaces, Crit Rev Microbiol
• 2013
  Pneumopathie d’hypersensibilité : diversité des agents étiologiques et démarche diagnostique, EMC Biologie Médicale
• 2013
  Fungal food choices of Dermatophagoïdes farinae affect indoor fungi selection and dispersal, Int J Environ Health Res
• 2013
  Chapitre 3. La maladie du Poumon de fermier, Ed. Lavoisier
• 2013
  Detecting and quantifying mites in domestic dust: a novel application for real-time PCR, Environ Intern J
• 2012
  Jewelry boxes contaminated by Aspergillus oryzae: an occupational health risk?, J Occup Env Hyg
• 2012
  Factors Influencing the Microbial Composition of Metalworking Fluids and Potential Implications for Machine Operator's Lung, Appl Env Microbiol
• 2012
  Contribution of a cyclonic-based liquid air collector for detecting Aspergillus fumigatus by QPCR in air samples, J Occup Environ Hyg
• 2012
  Recombinants antigens for serodiagnosis of farmer’s lung disease, JACI
• 2012
  Microbiological evaluation of ten French archives and link to occupational symptoms, Indoor air
• 2012
  Health effects of occupational exposure in a dairy food industry, with a specific assessment of exposure to airborne lactic acid bacteria, J Occup Env Med
• 2012
  Indoor dust and air concentrations of endotoxin in urban and rural environments, Let Appl Microb
• 2011
  Hypersensitivity pneumonitis and metalworking fluids contaminated by Mycobacteria, Eur Respir J
• 2011
  Exposure to moulds and actinomycetes in Alpine farms: a nested environmental study of the PASTURE cohort, Environ Res
• 2011
  Immuno-reactive proteins from Mycobacterium immunogenum useful for serodiagnosis of metalworking fluid hypersensitivity pneumonitis, Int J Med Microbiol
• 2011
  Response to the Letter of Barber CM et al. about “Hypersensitivity pneumonitis and metalworking fluids contaminated by Mycobacteria”, Eur Respir J
• 2011
  Variable beta-glucans production by different states of Eurotium amstelodami explains differences in inflammatory responses in airway cells., APMIS
• 2010
  Comparison of three antigenic extracts of Eurotium amstelodami in farmer’s lung disease serological diagnosis, Clin & Vacc Immun
• 2010
  Detection of Aspergillus fumigatus by QPCR in air samples impacted on low-melt agar, Am J Infect Control
• 2010
  New evidence of the involvement of Lichtheimia corymbifera in farmer’s lung disease, Med Mycol
• 2010
  Hypersensitivity pneumonitis due to moulds in a saxophone player, Chest
• 2009
  Chapitre 96. Pneumopathies d’Hypersensibilité, Médecine-Sciences Flammarion
• 2009
  Analysis of fungal contamination in unhealthy and in allergic-patient housing by real time PCR, Let Appl Microb
• 2009
  Indoor mould concentration in Eastern France, Indoor air
• 2009
  High levels of grass pollen inside European dairy farm : a role for the allergy protective-effects of environment, Allergy
• 2009
  Multilevel analysis of the impact factors and agricultural practices on the concentration in hay of microorganisms responsible for farmer’s lung disease, Ann Envir Agric Med
• 2008
  Characteristics of dwellings contaminated by moulds, J Environmental Monitoring
• 2007
  Diagnostic value of serum precipitins in active hypersensitivity pneumonitis, Eur Respir J
• 2007
  Assessment of four serological techniques in immunological diagnosis of farmer’s lung disease, J Med Microbiol
• 2007
  Impact of agricultural practices on microbiology of hay, silage and flour in Finnish and French farms, Ann Envir Agric Med
• 2007
  Decreasing Airborne Contamination Levels in High-Risk Hospital Areas Using a Novel Mobile Air-Treatment Unit, Inf Control Hosp Epid
• 2006
  Medical Radiology-Imaging of Occupational and Environmental Disorders of the Chest. Chapitre 3.5 Immunological Methods, Springer-Verlag
• 2005
  Pneumopathies d’hypersensibilité en milieu professionnel, EMC-Toxicologie Pathologie
• 2005
  Farmer’s lung disease and microbiological composition of hay: a case-control study, Mycopathologia
• 2005
  Evaluation of salting as a hay preservative against farmer’s lung disease agents, Ann Envir Agric Med
• 2004
  Cutaneous Alternaria infection in renal transplant recipients : a report of two cases with an unusual mode of transmission, Transpl Infect Dis
• 2004
  Microbiological evolution of hay and relapse in patients with farmer’s lung, J Occup Env Med
• 2002
  Influence of buffered propionic acid on the development of micro-organisms in hay, Mycoses
• 2001
  Role of Molds in farmer’s lung disease in Eastern France, Am J Respir Crit Care Med
• 2001
  Longitudinal Study of Anti-Candida albicans Mucosal Immunity against Aspartic Proteinases in HIV-Infected Patients, J Acquir Immune Defic Syndr
• 1999
  Identification of Fusarium species involved in human infections by 28s rDNA sequencing, J Clin Microbiol
• 1994
  Fluconazole Resistant recurrent oral Candidiasis in human immunodeficiency virus positive patients: persistence of Candida albicans strains with the same genotype, J Clin Microbiol
• 1991
  Influence of mode of storage and drying of fodder on thermophilic actinomycete aerocontamination in dairy farms of the Doubs region of France, Thorax

Grants and Contracts

• 2017
  Embrase

  Role:

  co-investigateur

  Funding Source:

  Agence Nationale de la Recherche

• 2017
  prévention des infections fongiques et patients d’hématologie

  Role:

  Chef de projet

  Funding Source:

  PRSE III Bourgogne Franche-Comté

• 2016
  Mic-Balistic

  Role:

  Chef de projet

  Funding Source:

  Société Francaise de Pneumologie de Langue Française

• 2015
  IgE Probiotic

  Role:

  Chef de Projet

  Funding Source:

  ZAAJ

• 2012
  Icode

  Role:

  Chef de projet

  Funding Source:

  ADEME /ANSES

• 2012
  Airfustox

  Role:

  co-investigateur

  Funding Source:

  ANSES

• 2011
  EBRA-ELFE

  Role:

  Chef de projet

  Funding Source:

  ANSES, Région Franche-Comté, INED

• 2011
  Fungicopd

  Role:

  co-investigateur

  Funding Source:

  PRSE II Région Nord

• 2011
  dust ADN

  Role:

  co-investigateur

  Funding Source:

  ANSES

• 2011
  Plates-formes de compostage

  Role:

  co-investigateur

  Funding Source:

  INRS

• 2011
  Direction Générale de la Santé et la Direction Régionale des Affaires Sanitaires et Sociale de Franche-Comté

  Role:

  Chef de projet

  Funding Source:

  PRSE II Franche-Comté

• 2011
  Ficqs Hémato

  Role:

  co-investigateur

  Funding Source:

  ARS Franche-Comté

• 2009
  SOPHIA

  Role:

  co-investigateur

  Funding Source:

  PHRC National

• 2009
  probiotiques

  Role:

  co-investigateur

  Funding Source:

  ANSES

• 2008
  Mycotox

  Role:

  co-investigateur

  Funding Source:

  ANSES

• 2008
  Foxing

  Role:

  co-investigateur

  Funding Source:

  Université Paris VI

• 2008
  Pasture Microbio

  Role:

  co-investigateur

  Funding Source:

  Consortium Pasture Projet européen

• 2007
  STEFI

  Role:

  co-investigateur

  Funding Source:

  INRS

• 2007
  Odiphaar

  Role:

  co-investigateur

  Funding Source:

  INTERREG

• 2006
  PHS ICAD

  Role:

  co-investigateur

  Funding Source:

  Agence Nationale de la Recherche

• 2005
  Moisissures dans les logements

  Role:

  Chef de projet

  Funding Source:

  Direction Générale de la Santé et la DRASS de Franche-Comté

Professional Memberships

• Membre de la Société Française de Mycologie Médicale (1994), élu au conseil (2007-2013), Secrétaire Général Adjoint (2010)
• Groupe de travail « compostage » ADEME (2002-2003)
• Groupe de travail « Habitat et moisissures » DGS/ Conseil Sup. Hyg. Publ. de Fr (2003-2006)
• Groupe de travail « ELFE » (Etude Longitudinale Française depuis l’Enfance), suivi sanitaire de 20 000 enfants pendant 18 ans (2006-actuel)
• Groupe de travail « risque biologique » INRS (2007-2009)
• Groupe de travail « Moisissures dans le bâti », Anses (Agence Nat. Sécurité Sanitaire, alimentation, environnement, travail (2014-2016)
• Groupe de travail « Risques dans l’agriculture », American Thoracic Society (2014-2017)
• Groupe de travail « Polluants biologiques de l'air ambiant en outre-mer », Anses (Agence Nat. Sécurité Sanitaire, alimentation, environnement, travail (2016-2017)