I am a Principal Investigator of a lab that investigates heart failure. Our group focuses on the molecular basis of heart failure, and the impact of elements like sex and ageing on heart failure. In collaboration with our colleagues in veterinary cardiology we have conducted research into a naturally occurring form of heart failure called 'dilated cardiomyopathy' (DCM). Almost half of all Doberman Pinschers die from DCM. The similarities between canine heart failure and human heart failure allows us to apply our research in both human and veterinary medicine. Our research into the fundamental science behind heart failure has lead to novel lines of investigation including biomarkers for the identification of heart failure in its early stages, and new molecular therapies for failing hearts.