Guilherme Pessoa-Amorim

I am a DPhil student at the Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU) within Oxford Population Health (University of Oxford). My DPhil project is funded by the Medical Research Council and will determine the feasibility of using routinely collected data on drugs dispensed to patients as a primary source of information about medications for participants in large-scale randomised controlled trials.

I began my academic career in 2019 when I joined CTSU to work in the AMALFI trial, a study which aims to shed light on the burden of subclinical atrial fibrillation in elderly high-risk patients. I am also part of the clinical team for the ORION-4 trial, a study which is assessing the effect of inclisiran, a novel cholesterol-lowering therapy, on cardiovascular events on patients with established atherosclerotic disease. More recently, I joined the RECOVERY trial, the largest randomised controlled trial of new treatments for patients hospitalised with COVID-19.

My main clinical and research interests are within the cardiovascular field, but I am generally also interested in the development of application of data-driven methodology for large randomised trials that can help us streamline the deployment of effective medical treatments and interventions

Besides my research work, I do regular clinical work as a junior doctor in Acute General Medicine at the Oxford University Hospitals NHS Foundation Trust