Dr. Yaffe’s research is directed toward development and improvement of imaging techniques for the detection, diagnosis and treatment of cancer, with a strong focus on breast cancer. His team is also interested in methods for analyzing image patterns to predict breast cancer risk and using these as tools to study the causes of breast cancer and to help develop preventive measures.
Activities in the lab range from developing image-processing strategies for improving the quality of diagnostic images and methods of quantifying the quality of medical images, to developing and evaluating 3-D imaging (tomosynthesis) and contrast-enhanced imaging methods.
His team has established a comprehensive program in biomarker imaging research, which includes development of new techniques for 3-D pathology. These techniques will be used for validation of new in vivo imaging methods, as well as for investigating approaches to improving accuracy of pathology, and adding prognostic and predictive information in management of cancer.