The underlying theme of Matthew's career has been to understand and facilitate human behaviour change, particularly behaviour change that is fundamental to addiction recovery. His current research is looking to understand the high rates of sexual HIV risk behaviour associated with certain abused drugs (e.g., cocaine, methamphetamine, alcohol).
Another focus of his research involves laboratory studies determining the behavioural and psychological effects of psychoactive drugs in humans, particularly novel or atypical drugs.
Current research with psilocybin is examining its potential for facilitating behaviour change.