Director MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University

My main interest is in the genetics of major psychiatric and neurodegenerative disorders. I am closely involved in research programmes on schizophrenia, bipolar disorder, Alzheimer’s disease, ADHD and depression, and in the relationship between 22q11 deletions and psychosis.

My work uses a combination of molecular genetic approaches including genome-wide association, copy number variant analysis and second generation sequencing to identify the specific genetic variants that confer risk to psychiatric and neurodegenerative disorders. I am increasingly interested in the impact of genetic discoveries on the understanding of disease mechanisms and classification.