Penghua Wang

My laboratory is interested in host-virus interactions, with a focus on RNA viruses in vivo and in vitro. Specifically, we attempt to understand pathogenic mechanisms of viral infection at the cellular and animal levels, and study the molecular function of host genes that influence viral pathogenesis and the disease outcomes. On the host end, we are keen on the innate immune system, detection of viruses and initiation of innate antiviral immune responses. On the viral end, we hope to understand the mechanisms of immune evasion and modulation of cellular functions by viral proteins.